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SUMMARY:Microfluidic Platforms for Controlling the in vitro Cellular Micro
 environment
DTSTART:20130705T130000
DTEND:20130705T140000
DTSTAMP:20260406T210240Z
UID:171971e66f668c71cecccf80bf2b515473244186ff7d03bd4844dbef
CATEGORIES:Conferences - Seminars
DESCRIPTION:Francesco Piraino\, Ph.D.\, Broad Institute\, MIT and Harvard 
 University\, Cambridge\, MA (USA)\nBio: Francesco Piraino received his B.S
 c. and M.Sc. degrees in Biomedical Engineering from Politecnico di Milano.
  During his master studies he spent a semester at the City University of N
 ew York\, under Dr. Tarbell’s supervision. He started his doctoral studi
 es in January 2009 and in December 2009 he was awarded a Progetto Roberto 
 Rocca Fellowship to join the Brigham & Women’s Hospital and Harvard-MIT 
 Division of Health\, Science and Technology\, supervised by Dr. Khademhoss
 eini. He received his PhD in Biomedical and Biomechanical Engineering in M
 arch 2012 from the Interpolytechnic School of Doctorate. He is now a Post-
 doctoral Associate at the Broad Institute of MIT and Harvard. His current 
 research focuses on the development of droplet microfluidic devices for si
 ngle-cell high-throughput screening.\nThe cellular microenvironment provid
 es cells with physical architecture\, soluble and adhesive signals\, growt
 h factors\, nutrients\, inhibitor chemicals\, and cell-cell interactions. 
 The in vivo cellular microenvironment is composed of an intricate mixture 
 of extracellular matrix proteins\, proteoglycans\, small molecule signals 
 and various adjacent cell types. These vary in space and time due to mater
 ial deformation\, fluid flow\, chemical reactions\; or cell proliferation\
 , differentiation\, death\, and migration. Cells continually sense these i
 nputs\, process the information and execute a behavior. Therefore\, to stu
 dy cells under well-controlled conditions in vitro or to manipulate cells 
 for clinical applications\, it is important to recreate the physiological 
 microenvironment.\nIn this seminar\, microfluidic platforms for applicatio
 ns including drug and material screening\, and high-throughput cell analys
 is will be discussed.
LOCATION:SV1717a http://map.epfl.ch/?room=sv1717a
STATUS:CONFIRMED
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