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SUMMARY:Evolutionary dynamics and ecophysiology of Microbial reductive deh
 alogenation
DTSTART:20110317T160000
DTSTAMP:20260509T054141Z
UID:8d2b765db777694bf89ef40d71201a29b5177c68915d2d15373ba0ae
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Alfred Spormann\, Departments of Chemical Engineering and o
 f Civil/Environmental Engineering\, Stanford University\, CA\, USA\nVinyl 
 chloride is a widespread groundwater pollutant and Group 1 carcinogen. A p
 revious comparative genomic analysis revealed that the vinyl chloride redu
 ctase operon\, vcrABC\, of Dehalococcoides sp. strain VS is embedded in a 
 horizontally-acquired genomic island that integrated at the single-copy ge
 ne ssrA. Dehalococcoides are members of the ‘rare biosphere’ with slow
  growth rate and are highly adapted to niches\, revealing a biology that i
 s distinct from the well-studied gamma proteobacteria. This talk will disc
 uss the biology as well as the\nimplications of the finding that the vcrAB
 C-containing genomic islands are a recentlyacquired subset of a diverse co
 llection of ssrA-specific mobile elements. These elements are a major cont
 ributor to strain-level diversity in Dehalococcoides\, and may have been s
 o throughout its evolution. The high similarity between vcrABC sequences i
 s quantitatively consistent with recent horizontal acquisition driven by 1
 00 years of industrial pollution with chlorinated ethenes.
LOCATION:AI1153
STATUS:CONFIRMED
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