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SUMMARY:BMI LEN Seminar - “Bidirectional optogenetic control of motoneur
 on  and muscle activity"
DTSTART:20130902T130000
DTSTAMP:20260508T120346Z
UID:98e68d40e289319d51a727a77e1f614c8fe55eb34c9b56c3d127dac7
CATEGORIES:Conferences - Seminars
DESCRIPTION:Abstract\nOptogenetics employs light-sensitive proteins\, call
 ed opsins\, expressed in neuronal membranes to facilitate optical excitati
 on or inhibition of neurons. Our laboratory is investigating applications 
 of optogenetics in the peripheral nervous system using transgenic and vira
 l approaches for delivery of opsins to targeted peripheral neurons. I will
  describe both optical excitation and inhibition of motoneurons measured i
 n muscle force and electromyographic activity as well as our methods for c
 ontrolling motoneuron activity in awake and freely moving rodents. These a
 pproaches can be broadly applied to study neuromuscular control and provid
 e therapeutic insights into disorders of the peripheral nervous system.
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153
STATUS:CONFIRMED
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