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SUMMARY:How to Make Complex Molecules from Simple Starting Material: the P
 alladium\, a Powerful Tool
DTSTART:20131127T171500
DTEND:20131127T183000
DTSTAMP:20260407T064318Z
UID:09c310cc14b1202340a95ccdce085277ffd06a85fd1da08880cf4eb1
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Jean Suffert\, Directeur de Recherche at CNRS\, Group Lead
 er\, Faculté de Pharmacie\, Illkirch\, France\nIn addition to molecular c
 omplexity\, the challenge of the chemist today is also the quest for effic
 iency of the synthetic route and maximization of structural complexity. Ou
 r laboratory investigations focus for several years on the study of an unp
 recedented cascade reaction involving a rare 4-exo-dig cyclocarbopalladati
 on followed by a terminated cross-coupling with an organometallic reagent.
  A 6- or 8-electrocyclization can occur leading to new tricyclic str
 uctures. The seminar will show that we can offer an easy access to complex
  polycyclic molecules resulting from readily available simple starting mat
 erials. Eventually\, it will be possible to propose the elaboration of a l
 arge collection of unprecedented structurally novel molecules based on rec
 ent promising results. Below are represented several complex structures th
 at has been prepared through the powerful 4-exo-dig cyclocarbopalladation.
  Many other extension of this method have not been so far explored and can
  afford a multitude of new and original scaffolds.
LOCATION:BCH 2218 https://plan.epfl.ch/?room==BCH%202218
STATUS:CONFIRMED
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