BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Memento EPFL//
BEGIN:VEVENT
SUMMARY:Bioimaging at the nanoscale: Single-molecule and super-resolution 
 fluorescence
DTSTART:20130920T140000
DTEND:20130920T153000
DTSTAMP:20260511T094902Z
UID:fefb19576fd815c232bf4658afb58e2da54fd51273a18fefe45a7557
CATEGORIES:Conferences - Seminars
DESCRIPTION:Pr. Xiaowei Zhuang (Harvard)\nDissecting the inner workings o
 f a cell requires imaging methods with chemical specificity\, single-mole
 cule sensitivity\, molecular-scale resolution\, and dynamic imaging capabi
 lity such that molecular interactions inside the cell can be directly vis
 ualized. Fluorescence microscopy is a powerful imaging modality for cell 
 biological research largely owning to its molecular specificity and dynami
 c imaging capability. However\, the spatial resolution of light microscop
 y\, classically limited by diffraction to a few hundred nanometers\, is s
 ubstantially larger than typical molecular length scales in cells. Hence m
 any subcellular structures and dynamics cannot be resolved by conventiona
 l fluorescence microscopy. We recently developed a super-resolution fluor
 escence microscopy method\, stochastic optical reconstruction microscopy 
 (STORM)\, which has allowed fluorescence imaging with molecular-scale reso
 lution and enabled discoveries of novel sub-cellular structures. In this 
 talk\, I will describe STORM and other singlemolecule imaging methods exp
 lored in the lab\, focusing on recent biological discoveries enabled by th
 ese high-resolution imaging approaches.
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153
STATUS:CONFIRMED
END:VEVENT
END:VCALENDAR