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SUMMARY:Genetic approaches to mouse brain circuit mapping and cell type ch
 aracterization
DTSTART:20131007T133000
DTEND:20131007T143000
DTSTAMP:20260509T191305Z
UID:a1d482f86238dbe452eb512a063621b1f9bd1163f81785d0a9888830
CATEGORIES:Conferences - Seminars
DESCRIPTION:Hongkui Zeng\, Allen Institute for Brain Science\, Seattle\, 
 WA\, USA\nThe brain circuit is an intricately interconnected network of a 
 vast number of neurons with diverse molecular\, anatomical and physiologic
 al properties. We have been working on developing technologies that will e
 nable the identification\, labeling\, monitoring and manipulation of diffe
 rent neuronal cell types\, and on using a combined molecular\, genetic and
  physiological approach to unravel the diversity and connectivity of the n
 euronal cell types that compose of neural circuits. In the Transgenic Tech
 nology program\, we build transgenic mouse lines that target sensors and e
 ffectors to specific types of neurons. In the Mouse Cell Types program\, w
 e use the mouse visual system as a model to systematically characterize th
 e transcriptomic\, morphological\, and electrophysiological properties of 
 different kinds of neurons\, towards a systematic taxonomy of cell types f
 or this circuit. Finally\, we wish to gain a comprehensive and detailed un
 derstanding of how different types of neurons are connected to each other.
  The Mouse Brain Connectivity Atlas project represents the first of such l
 arge-scale efforts\, in which axonal projections from different regions an
 d different cell types within these regions are systematically mapped thro
 ughout the brain to generate a 3D whole-brain projectome.
LOCATION:BC 420 https://plan.epfl.ch/?room==BC%20420
STATUS:CONFIRMED
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