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SUMMARY:Mobile Biosensors for Distributed Healthcare
DTSTART:20131017T110000
DTSTAMP:20260925T061632Z
UID:6888f244d157072a8d543abd216b462c1e23988bc8864ec00fc406bd
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Tony Turner\, Linköping University\, Sweden\nBio: Profe
 ssor Tony Turner’s name is synonymous with the field of Biosensors. He l
 ed the group which developed the world’s most successful type of biosens
 or\, the hand-held mediated amperometric glucose sensor for people with di
 abetes. In November 2010\, he moved his research activities to Sweden to h
 ead the Biosensors and Bioelectronics Centre at Linköping University\, wh
 ile continuing to advise Cranfield University on innovation. He was electe
 d a Fellow of the Royal Society of Chemistry (1996) and awarded a Higher D
 octorate (DSc) for his exceptional contribution to biosensors by the Unive
 rsity of Kent (2001) and an Honorary DSc by the University of Bedfordshire
  (2008).  He was admitted to the USA National Academy of Engineering as a
  Foreign Associate in 2006\, for his work on glucose sensors\, environment
 al monitors and synthetic recognition molecules. He recently won the Theop
 hilus Redwood Medal\, from the Royal Society of Chemistry (UK)\, for his o
 utstanding contribution to Analytical Science\, and the Acharya Vinova Int
 ernational Award (India) for his “notable and outstanding contribution i
 n the field of Biosensors and Bioelectronics”. Professor Turner has >750
  publications and patents in the field of biosensors and biomimetic sensor
 s and an h-index of 62. He co-founded and has edited the principal journal
  in the field\, Biosensors & Bioelectronics\, since 1985 and edited the fi
 rst textbook on Biosensors in 1987.  In addition to advising companies an
 d governments worldwide in the general area of analytical biotechnology\, 
 he has served as an expert witness in patent litigations on three continen
 ts.\nThis lecture will consider how the recent emergence of printed bioele
 ctronics can offer new solutions to distributed diagnostics for the mainte
 nance of wellbeing\, management of an ageing population\, food security an
 d environmental safety.\nThe adaptation of screen printing for the product
 ion of enzyme electrodes proved to be a decisive element in the success of
  mediated electrochemical devices in the home blood-glucose monitoring mar
 ket. Until then\, biosensors had been wholly hand made\, and could not pos
 sibly address a market requiring billions of devices a year. Coupled with 
 the use of proprietary mediators and patented capillary-fill designs\, mac
 hine fabrication of enzyme electrodes enabled the paradigm changing switch
  to the electrochemical devices that now dominate this market. Today\, app
 roximately half of the electrodes used in disposable glucose sensors are s
 creen printed using curable polymer inks\, while the remainder are produce
 d using a combination of vapour deposition of thin layers of metal such as
  palladium\, followed by laser ablation to pattern these into individual e
 lectrodes. Additional printing steps\, drop-on-delivery and /or lamination
  results in a final sensor\, which can cost around 2-6 US cents / strip to
  make\, when produced by the millions. However\, it is now timely to chall
 enge our original paradigm of a disposable strip coupled to a pocket-sized
  meter. Even in bulk\, the average meters cost between US$7-10 to manufact
 ure\, with some more elaborate versions costing as much as US$90.\nSo why 
 not print the whole device? All-printed Mn –ZnO batteries can already be
  made to power microsensors and for other applications such as RFID tags\,
  transdermal drug delivery\, cosmetic patches and smart packaging. These a
 re available as commercial products such as the SoftBattery™ from Enfuce
 ll (Finland). Monochrome emissive or reflective digital displays can be pr
 inted on both paper and plastic and\, in keeping with the trend to interfa
 ce biosensing systems with telecommunication\, thin film aluminium or copp
 er antennae are also available. A state-of-the-art combination of these te
 chnologies allows us to formulate an all-printed sensing instrument where 
 everything is produced on a simple sheet of PET to form a disposable\, cre
 dit-card like device. An example of such a working demonstrator resulting 
 from collaboration between Acreo ICT AB and our team at Linköping Univers
 ity is shown below. Analyte concentration can be measured in a few seconds
  and observed via the printed display\, with the device being powered by a
  printed battery. This platform is being used to develop a range of new pr
 oducts incorporating nanomaterials\, principally for medical diagnostics\,
  but also for food safety analysis\, environmental monitoring and security
  applications.\nIn addition to reviewing the evolution of printing technol
 ogy in this arena\, this talk will explore the multifarious sensing config
 urations that can be supported by this inexpensive and disposable platform
 . Graphene-based hybrid structures\, unsubstituted phenothiazines and Prus
 sian blue nanoparticles have recently been incorporated into novel sensors
  for metabolites and physiologically important enzymes. Electrochemical im
 munosensors have also been formulated using silver nanoparticles and in la
 bel-free formats. Gold nanoparticles and nanostructured gold surfaces prov
 ide further functional enhancement and smart polymers can add reversibilit
 y to affinity systems and modulation to catalytic configurations. Finally\
 , synthetic receptors based on imprinted nanoparticles offer robustness be
 yond that normally achieved with biological components. The combination of
  advanced synthetic materials with biologically inspired constituents prom
 ises to facilitate a growth in personalised analytical solutions that are 
 widely available to the consumer and that can capitalise on the ubiquitous
  telecommunications and information systems that are now both widely avail
 able and rapidly evolving.
LOCATION:Salle "la Musicienne"  Rue Jaquet-Droz 1\, 2000 Neuchâtel
STATUS:CONFIRMED
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