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SUMMARY:Minimally invasive glucose measurement based on interstitial fluid
  extracted transdermally
DTSTART:20131104T114000
DTEND:20131104T120000
DTSTAMP:20260925T073453Z
UID:0033b21a864b9154b0bdb92764a93a0798ffcc34e51eacf4681b24db
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Dachao Li (Tianjin)\nEPFL/IMT - Peking University worksh
 op on MEMS and related technologies\nIn diabetes care\, continuous glucose
  monitoring of interstitial fluid (ISF) in subcutaneous tissue allows time
 ly detection and correction of abnormal blood glucose excursions. This can
  be effectively achieved by measuring glucose concentrations in transderma
 lly extracted ISF samples. Recently\, MEMS technology has been used to pro
 duce miniaturized devices for transdermal ISF extraction and glucose sensi
 ng\, but there is a lack of on-chip ISF volume measurement capabilities\, 
 which are required to compensate for skin permeability variations over tim
 e. The enzymatic electrochemical sensor has been commonly realized for glu
 cose monitoring\, in which electroactive chemical generation and hydrogen 
 peroxide production may cause erosion of the sensor electrodes and deactiv
 ation of the functional enzymes. Also\, integration of transdermal ISF ext
 raction and glucose sensing within a single MEMS device has yet to be real
 ized. Here we address these limitations by integrating ISF transdermal ext
 raction\, ISF volume measurement\, and optical or dielectric glucose sensi
 ng in a single lab-on-a-chip system. The single-chip device can potentiall
 y enable automated\, accurate\, and continuous monitoring of subcutaneous 
 ISF glucose concentrations.Biography:\nDr. Dachao Li received his Ph.D. de
 gree majoring in Precision Instrument and Mechanics at Tianjin University 
 in China in 2004. Then he conducted postdoctoral research at Peking Univer
 sity in China and Case Western Reserve University in USA respectively from
  2004 to 2008. Presently\, he is an associate professor at the College of 
 Precision Instrument and Optoelectronics Engineering in Tianjin University
 . His research interests include micro sensors and biomedical micro system
 s.
LOCATION:Vittoz https://epfl.doodle.com/pdq533ay9ek9u7dw
STATUS:CONFIRMED
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