BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Memento EPFL// BEGIN:VEVENT SUMMARY:Droplet Microfluidics: Screening\, Amplification and Dilution on t he Microscale DTSTART:20131206T131500 DTSTAMP:20260508T135744Z UID:c8cd8b9fbe8e941ee3f609e892bb95b077c8af6dfb5ef87731ce24dc CATEGORIES:Conferences - Seminars DESCRIPTION:Prof. Andrew J. deMello\, ETH Zürich (CH)\nBio: Andrew deMell o is currently Professor of Biochemical Engineering in the Department of C hemistry and Applied Biosciences at ETH Zurich. Prior to his arrival in Zu rich he was Professor of Chemical Nanosciences and Head of the Nanostructu red Materials and Devices Section in the Chemistry Department at Imperial College London.\nHe obtained a 1st Class Degree in Chemistry and PhD in Mo lecular Photophysics from Imperial College London in 1995 and subsequently held a Postdoctoral Fellowship in the Department of Chemistry at the Univ ersity of California\, Berkeley working with professor Richard Mathies.\nH is research interests cover a broad range of activities in the general are a of microfluidics and nanoscale science. Primary specializations include the development of microfluidic devices for high-throughput biological and chemical analysis\, ultra-sensitive optical detection techniques\, nanofl uidic reaction systems for chemical synthesis\, novel methods for nanopart icle synthesis\, the exploitation of semiconducting materials in diagnosti c applications\, the development of intelligent microfluidics and the proc essing of living organisms.\nAndrew has given approximately 250 invited le ctures at conferences and universities in North America\, Europe\, Africa and Asia (including 50 plenary or keynote lectures)\, has published 170 pa pers in refereed journals\, and co-authored two books. He currently sits o n the Editorial Boards of Chemistry World\, The Journal of Flow Chemistry\ , Biomicrofluidics\, BioChip journal and Imperial College Press. He is als o co-founder of Molecular Vision Ltd\, an Imperial College spin-out compan y developing low-cost diagnostic devices for use in the doctor's surgery a nd in the home.\nScience originating from the deMello group has been recog nized through the award of the 2002 SAC Silver Medal (Royal Society of Che mistry)\, the 2009 Clifford Paterson Medal from The Royal Society\, the 20 09 Corday Morgan Medal (Royal Society of Chemistry) and the 2007 Clark Mem orial Lectureship (California State University).\nAbstract:\nThe past 15 y ears have seen considerable progress in the development of microfabricated systems for use in the chemical and biological sciences. Interest in micr ofluidic technology has in large part been driven by concomitant advances in the areas of genomics\, proteomics\, drug discovery\, high-throughput s creening and diagnostics\, with a clearly defined need to perform rapid me asurements on small sample volumes. At a basic level\, microfluidic activi ties have been stimulated by the fact that physical processes can be more easily controlled when instrumental dimensions are reduced to the micron s cale.\nThe relevance of such technology is significant and characterized b y a range of features that accompany system miniaturization. Such features include the ability to process small volumes of fluid\, enhanced analytic al performance\, reduced instrumental footprints\, low unit costs\, facile integration of functional components within monolithic substrates and the capacity to exploit atypical fluid behaviour to control chemical and biol ogical entities in both time and space. Based on these advantageous charac teristics\, microfluidic systems have been used to good effect in a wide v ariety of applications including nucleic acid separations\, protein analys is\, process control\, small-molecule synthesis\, DNA amplification\, immu noassays\, DNA sequencing\, cell manipulations\, nanomaterial synthesis an d medical diagnostics.\nMy lecture will describe recent studies that are f ocused on exploiting the spontaneous formation of droplets in microfluidic systems to perform a variety of analytical processes. Specifically I will report on how nanoliter-sized droplets can be used as an effective tool i n coupling two-dimensional analytical separations in both time and space. Additionally\, I will describe a new technique for high-throughput dilutio n and screening of nanoliter-sized droplets in microfluidic channels. LOCATION:SV1717A http://map.epfl.ch/?room=sv1717a STATUS:CONFIRMED END:VEVENT END:VCALENDAR