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SUMMARY:The population genetics of adaptation
DTSTART:20110110T100000
DTSTAMP:20260916T065902Z
UID:7b905f600fb932a43cf59dc95eea34340c167a2dba25c8ba19c5d73f
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Jeffrey D. JENSEN\, Program Bioinformatics & Integrative Bi
 ology\, University Massachusetts\, Medical School\, Worcester\, MA\, USA\n
 Quantifying the relative roles of adaptive and non-adaptive processes in t
 he evolution of natural populations is perhaps the most fundamental questi
 on in evolutionary biology\, and has been studied for well over a century.
  However\, this characterization remains remarkably elusive owing to diffi
 culties associated with uncoupling genomic signatures of selection from pa
 tterns produced by demographic factors (e.g.\, population size change and 
 structure). I will summarize recent theoretical and statistical advances o
 n this topic\, as well as highlight three recent applications of this rese
 arch\, each utilizing a different data class:\n1. Divergence: understandin
 g human evolution in the age of Neandertal genomics\n2. Polymorphism: char
 acterizing the evolution of adaptive coat color in wild mice\n3. Experimen
 tal: inferring the distribution of fitness effects by considering all poss
 ible point mutations in yeast
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153
STATUS:CONFIRMED
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