BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Memento EPFL//
BEGIN:VEVENT
SUMMARY:Microfluidics and Nanopatterning for Bioanalysis and Tissue Engine
 ering
DTSTART:20140716T140000
DTSTAMP:20260408T025926Z
UID:c2fbfb9dd36cbdedf6c1f282b03b7e43f3fbd420c7f1032f59775a7e
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. David Juncker\, McGill University\, Montréal\, QC (CAN)
 \nBIOENGINEERING SEMINARAbstract:\nThis presentation will cover recent adv
 ances from my lab. I will present (i) capillary microfluidics in Si chip a
 nd on thread\, and demonstrate basic function and how to build complex cir
 cuits\, and show that like in electronics\, capillary circuits can be asse
 mbled from elementary building blocks. Next\, I will discuss antibody micr
 oarrays and multiplexed immunoassays and explain how vulnerability to cros
 s-reactivity has thwarted efforts to scale up these arrays. I will present
  the scalable antibody colocalization microarray (ACM) and the snap chip f
 or microarray-to-microarray liquid transfer\, and show their use for high 
 sensitivity protein profiling and biomarker discovery for breast cancer in
  blood. In the second part of the presentation I will present a new framew
 ork for cell-surface interactions\, choice assays\, and migration\, with t
 he introduction of sets of standardized reference surfaces and cell-surfac
 e affinity curves. New micro- and nanocontact printing techniques will be 
 presented to universally pattern proteins on any surface with nanometer re
 solution. Results of neuronal haptotaxis on digital nanodot gradients with
  very high dynamic range will conclude this presentation.Bio:\nI was born 
 in Aarau\, a small city close to Zurich\, in the German part of Switzerlan
 d\, and moved to a small town close to Neuchâtel\, in the French part of 
 Switzerland at the age of twelve. I went on to study at the Institute of M
 icrotechnology of the French speaking University of Neuchâtel\, and recei
 ved a degree in Electronics–Physics in 1996.\nIn 1997\, I was awarded a 
 one-year traveling fellowship from the Swiss Academy of Engineering Scienc
 es and spent 16 months in Japan\, first learning some basic Japanese in th
 e beautiful city of Kanazawa\, and then staying 1 year as a visiting scien
 tist at the National Metrology Institute of Japan in Tsukuba\, working on 
 a microelectromechanical (MEMS) accelerometer.\nIn 1999 I moved back to th
 e the German speaking part of Switzerland and studied and worked at the IB
 M Zurich Research Laboratory until 2004. Between 1999 and 2002 I was study
 ing towards my PhD under the supervision of Dr. Emmanuel Delamarche (at IB
 M) while my official PhD advisor was Dr. Nico de Rooij from the Institute 
 of Microtechnology at the University of Neuchatel which awarded my PhD in 
 2002. During this time we developed and used soft lithography for high-res
 olution surface patterning with proteins and autonomous microfluidics that
  relied on capillary effects for both powering and controlling the flow of
  liquid. Between 2002 and 2004 we developed the microfluidic probe for loc
 al processing of surfaces and of cells\, and which constitutes a central t
 heme of our current research.\nFrom 2004 to 2005\, I was a postdoc in the 
 Micro- and Nanosystems group of Dr. Christofer Hierold at the Swiss Federa
 l Institute of Technology in Zurich (ETH). I helped setting up the lab\, i
 ntroduced polymer microfabrication and replication processes for making a 
 wireless implantable strain sensor.\nEnd of 2005\, I started as an assista
 nt professor in the Biomedical Engineering Department of McGill University
 \, an English-speaking institution in Montréal\, a French-English bilingu
 al city in Canada. In 2011\, I was promoted to the rank of associate profe
 ssor with tenure. in 2006\, I was been awarded a Canada Research Chair in 
 Micro- and Nanobioengineeringm which was renewed in 2011. In 2012\,I was s
 elected as Young Scientist by the IAP - the global network of science acad
 emies - and represented Canada at World Economic Forum\, Summer Davos New 
 Champions Meeting\, Tianjin\, China\, Sept 10-15th\, 2012.\nMy current int
 erest are in the exploration of miniaturization and integration in biology
  and medicine\, which includes the conception\, engineering and utilizatio
 n of novel micro and nanotechnologies for manipulating\, stimulating and s
 tudying oligonucleotides\, proteins\, cells\, and tissues. The emerging fi
 eld of nanobiotechnology\, in a broad sense\, is the most exciting to me\,
  and is also key to tackle some of the major challenges in biology and med
 icine\, for example identify novel biomarkers for early disease diagnosis 
 or develop low cost point-of-care diagnostics for multiple disease.
LOCATION:SV1717a http://map.epfl.ch/?room=sv1717a
STATUS:CONFIRMED
END:VEVENT
END:VCALENDAR