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SUMMARY:Presynaptic versus postsynaptic dopamine D2 receptor signaling and
  neurological/neuropsychiatric disorders  
DTSTART:20101027T140000
DTSTAMP:20260407T163426Z
UID:cf4d83b4ea762b023296ad3aba7df7cd415d1ff138eb4933ff13e824
CATEGORIES:Conferences - Seminars
DESCRIPTION:Emiliana BORRELLI\, Professor\, Dept Microbiology & Molecular 
 Genetics\, University of California Irvine\, USA \nDopamine is a major neu
 romodulator of brain functions as illustrated by the number of neurologica
 l (i.e. Parkinson’s disease) and neuropsychiatric (i.e. schizophrenia) d
 isorders that derive from dysregulation of dopamine signaling. \nOur labor
 atory has a longstanding interest in unraveling the complexity of dopamine
  D2 receptor (D2R)-mediated signaling\;  these receptors regulate dopamine
  synthesis\, release\, firing of dopaminergic neurons as well as postsynap
 tic responses related to intracellular signaling and regulation of other n
 eurotransmitters release. In addition\, D2Rs are the major target of antip
 sychotics\, indicating that D2R-mediated signaling is contributing to the 
 etiology of disorders such as schizophrenia.\nNovel findings will be prese
 nted\, which clarify the role of each specific D2R component in vivo.
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153
STATUS:CONFIRMED
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