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SUMMARY:The population genetics of adaptation
DTSTART:20141106T121500
DTEND:20141106T131500
DTSTAMP:20260406T170033Z
UID:95f4d151765817adebea4aa904488706f554eafb4214c8263cb44305
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Jeffrey Jensen\, EPFL/SV/ IBI-SV UPJENSEN\nUnderstanding th
 e relative frequencies and proportions of selective effects of newly arisi
 ng\, segregating\, and fixed mutations - central to population genetics ov
 er the last century - stands as a major focus of the present and future Je
 nsen Lab. This underlying question has inspired our approach integrating t
 oolsets from computer science\, mathematics and statistics with evolutiona
 ry biology\, medical and ecological genetics\, experimental evolution\, an
 d population genomics. I will here highlight our current and future work s
 tudying adaptively important mutations as they arise\, transit through the
  population\, and ultimately achieve fixation – discussing applications 
 ranging from mouse to yeast to influenza virus. Thus\, while our research 
 program is topically diverse in terms of approach and organism\, the domin
 ant and central underlying theme is the study of adaptation\, and the stro
 ngly coupled development of theoretical and statistical tools with novel d
 ata analysis. With these tools at our disposal\, I will make the case that
  population genetics is on the verge of important breakthroughs in both ou
 r general understanding of the process of adaptation\, but also in the abi
 lity of evolutionary analysis to provide important ecologically and clinic
 ally relevant insights to other research communities as well.
LOCATION:SV 1717A http://plan.epfl.ch/?lang=en&room=sv+1717a
STATUS:CONFIRMED
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