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SUMMARY:The NAD World: Systemic Control of Metabolism and Aging by SIRT1 a
 nd NAMPT-Mediated NAD Biosynthesis in Mammals 
DTSTART:20100820T114500
DTSTAMP:20260916T055302Z
UID:2e9eb8a31d730ee5f6388dfcb2af28f28047031a6bb1db4bd568aee5
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Shin-ichiro IMAI M.D\, Ph.D.\, Associate Professor\, Dept 
 Dev. Biology &  Medicine\, Univ Washington\, St Louis\, MO\, USA\nThe mamm
 alian NAD-dependent protein deacetylase SIRT1 and nicotinamide phosphoribo
 syltransferase (NAMPT)-mediated systemic NAD biosynthesis together play a 
 critical role in the regulation of metabolism and aging in mammals.  We ha
 ve proposed a comprehensive concept of a novel systemic regulatory network
  connecting metabolism and aging in mammals\, named the "NAD World."  The 
 aging-regulatory hierarchy of tissues/organs in the NAD World\, particular
 ly focusing on the function of SIRT1 in the hypothalamus\, will be discuss
 ed.
LOCATION:AI 1153 https://plan.epfl.ch/?room==AI%201153
STATUS:CONFIRMED
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