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SUMMARY:Interareal interactions in the sensorimotor network: from mechanis
 ms to interventions
DTSTART:20150204T120000
DTEND:20150204T130000
DTSTAMP:20260407T183713Z
UID:a37a0091c4dcf706d1f3fee10034dea521731a79786dc692c32bbfff
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof Friedhelm C. Hummel\, University Medical Center Hamburg-
 Eppendorf\, Hamburg\, Germany.\nThe integration of individuals into modern
  societies relies on their ability to dynamically adjust to a fast changin
 g environment. This holds especially true during advancing age\, parallele
 d by a decline in cognitive functions and the ability to acquire new skill
 s\, and after a focal brain lesion\, such as a stroke\, both impacting sig
 nificantly integration in social and professional life. For example\, comp
 lete motor recovery occurs in less than 15% of stroke patients. Residual d
 eficits of the hand function are a key impediment for reintegration in dai
 ly social and professional life. In the view of an aging society and 270.0
 00 strokes per year  in e.g.\, Germany\, predicted to increase up to 450.
 000/year in 2050\, it is of great importance to develop novel intervention
 al strategies to enhance functional recovery and age-declined cognitive fu
 nctions to warrant best integration and independence in society.  To achi
 eve these goals it is crucial to better understand adaptive and mal-adapti
 ve changes of the cerebral networks after a stroke and during healthy agin
 g.\nWithin the present talk an overview of current findings regarding (a) 
 changes of interareal interactions and connectivity of network hubs of the
  sensorimotor network determined by a multimodal systems neuroscience appr
 oach including paired-pulse TMS\, EEG\, structural and functional MR-imagi
 ng\, (b) modulation of hubs of the sensorimotor network by non-invasive br
 ain stimulation and its effects on motor functions\, including executive c
 ontrol and learning\, and (c) its underlying mechanisms will be provided. 
 At the end\, an outlook on promising future directions such as prediction 
 of recovery\, patient stratification for specific treatments\, or modellin
 g approaches will be discussed.\nBio: Friedhelm C. Hummel serves as the V
 ice Director of the Department of Neurology and the Co-Chairman of the Uni
 versity Sleep Laboratory of the University Medical Center Hamburg-Eppendor
 f\, Hamburg. He is the head of the BrainImaging and NeuroStimulation (BINS
 ) Laboratory\, and a leading expert in functional regeneration after strok
 e\, mechanisms of healthy aging\, interventional neuroscience and neuropla
 sticity. To this end\, he is using a multimodal systems neuroscience resea
 rch approach in humans\, including behavioral tasks focused on executive c
 ontrol and learning\, non-invasive brain stimulation\, functional and stru
 ctural imaging and modelling. Since 2013\, he is holding a guest professor
 ship at the Favoloro University\, Buenos Aires\, Argentina. He received gr
 ants from various funding organizations\, including the German\nResearch F
 oundation (DFG)\, the German Ministry for Research and Education (BMBF) an
 d the Humboldt-Foundation (AvH). So far\, he published more than 100 resea
 rch papers in excellent international peer-reviewed journals and book chap
 ters\, is participating in several study boards as reviewer of different f
 unding organizations (e.g.\, HRC New Zealand\, Marsden Fund\, Raines Grant
 \, Welcome Trust\, Swiss National Fund\, Academie Louvain\, Finish Academy
  of Science)\, is ad hoc reviewer of several clinical and scientific journ
 als (such as Nat Neuroscience\, Lancet Neurology\, Curr Biol\, Ann Neurol\
 , Brain and others) and is member of the editorial boards of clinical and 
 neuroscientific journals (e.g.\, Experimental and Translational Stroke Res
 earch\, Frontiers in Neuroprosthetics). For his translational research\, h
 e received the FARE award of the National Institutes of Health\, Bethesda\
 , USA\; the Susanne Klein-Vogelbach-Preis zur Erforschung der menschlichen
  Bewegung\, the Dr. Martini Prize of the University of Hamburg and the Pri
 ze of the German Society of Neurotraumatology and Clinical Neurorehabilita
 tion.
LOCATION:SV1717a http://plan.epfl.ch/?room=SV1717a
STATUS:CONFIRMED
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