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SUMMARY:NIH-Biomechanisms of Peripheral Nerve Damage by Anti-Cancer Therap
 y (R21) 
DTSTART;VALUE=DATE:20150507
DTSTAMP:20260427T205912Z
UID:d9bf0820eda18c54315dbc90a42041581049a5e93cfe1a525758e561
CATEGORIES:Call for proposal
DESCRIPTION:NIH Agency\nThe purpose of this Funding Opportunity Announceme
 nt (FOA) is to encourage basic biologic research on damage to the peripher
 al nervous system instigated by pharmacologic cancer treatments\, known as
  chemotherapy-induced peripheral neuropathy (CIPN). The majority of acquir
 ed peripheral neuropathy research has focused on diabetic and inherited di
 seases\; this FOA intends to stimulate neuroscience researchers to apply t
 heir expertise from studying these other neuropathies to the injuries incu
 rred by cancer treatments. More data is necessary to understand the mechan
 isms of neuronal damage and to identify the targets instrumental to CIPN i
 nitiation and maintenance. Preclinical research that focuses not only on p
 eripheral neuropathic pain but also on neurosensory symptoms such as pares
 thesias and peripheral anesthesias is invited. The ultimate goal of this F
 OA is to lead to a molecular understanding of CIPN that allows for the rat
 ional development of interventions that will treat or prevention CIPN.
LOCATION:
STATUS:CONFIRMED
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