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SUMMARY:Probing the Soft Side with Nanoindentation Techniques
DTSTART:20100520T160000
DTSTAMP:20260414T211957Z
UID:25331d0f37d60c5fe3f725776a21adf2bdeffa15936273ee1d817604
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr Michelle L. Oyen\, Cambridge University\nAbstract :\nThe me
 chanical properties of many “soft” materials are of interest for biome
 dical applications\, including both natural tissues and hydrogels for tiss
 ue engineering applications. In the last 15 years\, nanoindentation techni
 ques have gained prominence in the mechanical testing community for three 
 reasons: first\, the fine resolution in load and displacement transducers\
 , second the fine spatial resolution for mapping local mechanical properti
 es\, and finally the relative ease of performing mechanical testing. In th
 e current studies\, we extend the scope of nanoindentation testing with co
 mmercial indenters to quantitative measurements on kPa materials. Differen
 t forms of the material constitutive response were considered with an emph
 asis on time-dependent viscoelastic or poroelastic deformation. Applicatio
 ns are the considered for hydrated tissues and hydrogels including articul
 ar cartilage\, bone and mechanically graded hydrogels. Further investigati
 ons using adaptations of these nanoindentation techniques examine nano-sca
 le adhesion and mechanical outcomes in stem cell differentiation. This stu
 dy demonstrates the potential for high-throughput mechanical screening of 
 soft materials and for mapping property gradients in inhomogeneous materia
 ls as these approaches can now be extended to materials in the kPa elastic
  modulus range.\n\nCo-workers :\nMatteo Galli\, Tamaryn A. V. Shean\, Kirs
 ty Main\, Wesley K. Chua\n\nBio :\nMichelle L. Oyen is a Lecturer in Mecha
 nics of Biological Materials in the Mechanics and Materials Division and t
 he Engineering for the Life Sciences group in the Cambridge University Eng
 ineering Department. She holds a B.S. degree in Materials Science and Engi
 neering and an M.S. Degree in Engineering Mechanics\, both from Michigan S
 tate University and a Ph.D. degree in Biophysical Sciences and Medical Phy
 sics from the University of Minnesota. She joined Cambridge Engineering in
  2006 following an appointment as Research Scientist at the University of 
 Virginia Center for Applied Biomechanics.
LOCATION:CO 017
STATUS:CONFIRMED
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