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SUMMARY:Spying on the inner workings of cells with super-resolution micros
 copy
DTSTART:20150413T161500
DTEND:20150413T171500
DTSTAMP:20260920T172024Z
UID:6ed07e05a6bb46d67cd18840d8653a12a3564188904925137e39336d
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Suliana Manley\, Lab. of experimental biophysics\, EPFL\
 nBio: From 06/2009 Tenure-track assistant professor\, EPFL\, Lausanne\, Sw
 itzerland\n2006-2009 Post-Doctoral fellow\, National Institutes of Health\
 , Bethesda\, MD\, USA\n2004-2006 Post-Doctoral fellow\, Massachusetts Inst
 itute of Technology\, Cambridge\, MA\, USA\n1999-2004 PhD (Physics) Awarde
 d 06/2004\, Harvard University\, Cambridge\, MA\, USA\n1993-1997 Bachelors
  (Cum Laude) Physics & Mathematics\, Rice University\, Houston\, TX\, USA\
 nOur primary goal is to use experiments to inform quantitative models for 
 the biophysics of protein assemblies\, in the cellular environment. Toward
  this goal\, we have developed super-resolution and single-molecule fluore
 scence imaging technologies. We have enabled automated 3D PALM acquisition
 \, developed algorithms for rapid and quantitative analysis\, and identifi
 ed better dyes and buffers for robust multicolor imaging. With these techn
 ological breakthroughs\, we have made several exciting biological findings
 . We showed that the bacterial division machinery is patchy across the cel
 l cycle and quantified its architecture for hundreds of cells\, constraini
 ng its potential role in generating force during cell division. We also re
 vealed the symmetry of the core centriolar protein complex\, a structure t
 hat is key to proper cell polarization and division. We are now poised to 
 take these studies to the next level with large-scale\, high throughput mi
 croscopy.
LOCATION:Room CE1 http://plan.epfl.ch/?lang=fr&zoom=20&recenter_y=5864182.
 50561&recenter_x=731299.44535&layerNodes=fonds\,batiments\,labels\,informa
 tion\,parkings_publics\,arrets_metro\,transports_publics&floor=1&q=ce1
STATUS:CONFIRMED
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