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SUMMARY:Enabling Single-Molecule Measurements with Microfluidics and Optic
 al Microresonators: Disordered Proteins and Semiconducting Polymers 
DTSTART:20150504T140000
DTSTAMP:20260503T014017Z
UID:b0fb52fa7d2e616fc24983e08e6d4ad5e175f651ca7b3c3b8dd58c31
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Randall H. Goldsmith\, University of Wisconsin\, Madison
 \, WI (USA)\nBIOENGINEERING SEMINARAbstract:\nSingle-Molecule measurements
  offer a wealth of detail about chemical diversity and unsynchronized dyna
 mics\, but only if the system under study is conducive to known methods of
  single-molecule fluoresence microscopy.  I will present two cases where 
 new measurement technology enables new observations on individual molecule
 s.  In the first case\, a microfluidic trap that cancels Brownian motion 
 will be used to explore the solution-phase conformation of an intrinsicall
 y disordered protein\, Tau\, central to the etiology of Alzheimer’s Dise
 ase.  In the second case\, a method to enable study of non-fluorescent mo
 lecules will be described using ultrahigh quality-factor optical microreso
 nators as platforms for spectroscopy.  This method will be applied to stu
 dy the electronic structure of doped conjugated polymers.Bio:\nB.A. 2002\,
  Cornell University\nPh.D. 2007\, Northwestern University (supervisor: W.E
 . Moerner)\nPostdoctoral Researcher at Stanford University
LOCATION:BM 5 202 http://map.epfl.ch/?room=bm5202
STATUS:CONFIRMED
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