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SUMMARY:INCF Infrastructure for Interoperable Atlases of Rodent Brain
DTSTART:20100322T161500
DTSTAMP:20260916T002732Z
UID:cf720d5f01622bfc5092f954c4aea00bbdc6e024a2fed106e68bd50c
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Ilya Zaslavsky\, San Diego Supercomputer Center\, Universi
 ty of California\, San Diego\, USA\nThe goal of the INCF Digital Atlasing 
 task force is to define a common framework for exchanging information betw
 een neuroscience atlases\, across scales\, modalities\, and semantic and s
 patial conventions of individual projects. The INCF digital atlasing infra
 structure (INCF-DAI) is envisioned as a collection of standard APIs and di
 stributed services that support publication\, discovery and invocation of 
 heterogeneous atlas resources. The initial phase of INCF-DAI focuses on in
 teroperability of mouse brain atlases\, specifically on different ways of 
 referencing spatial locations in the brain and transforming location infor
 mation between the atlases.\n\nMultiple renditions of mouse brain space ex
 ist\, including spatial referencing adopted in the Paxinos and Watson Atla
 s\, Allen Brain Atlas\, Edinburgh Mouse Atlas Project (EMAP) and the emerg
 ing Waxholm Space (WHS)\, currently being developed under the aegis of INC
 F as the target volume for a common spatial reference system. We seek to m
 ake these representations of space interoperable\, which includes: 1) form
 ally describing the available atlas coordinate systems\; 2) defining trans
 formations between WHS and other atlas coordinate systems\; 3) developing 
 a standard vocabulary/ontology for neural structures linked to spatial rep
 resentation of the structures\; 4) developing APIs for exchanging spatial 
 information between atlas data resources\, service middleware\, and client
  applications\; 5) defining a procedure for registering additional atlas c
 oordinate systems to the common framework\; 6) supporting spatial querying
  of multiple distributed atlas databases.\n\nThis presentation will review
  the progress to date\, including models of atlas coordinate reference sys
 tems and spatial transformations\, and service APIs for INCF atlas hubs an
 d the INCF central metadata repository. The spatial data integration conce
 pts will be illustrated using a novel 3D atlas viewer capable of communica
 ting the location of point of interest (POI) to the service layer\, and re
 trieving information from other atlas sources (e.g. anatomic feature names
 \, gene expressions\, image fragments\, correlation maps) available at the
  POI transformed to the respective coordinate system of the target atlas.\
 n\nIlya Zaslavsky directs Spatial Information Systems Lab at San Diego Sup
 ercomputer Center\, and leads the INCF Digital Atlasing Infrastructure Tas
 k Force (http://www.incf.org/about/programs/atlasing). 
LOCATION:AI 1-153
STATUS:CONFIRMED
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