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SUMMARY:Cell Geography: Organelles in their Natural Habitat
DTSTART:20150618T160000
DTSTAMP:20260916T044003Z
UID:6157065811edd9898b4b84feb9612aefb402ea0df9406448b874dc1e
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Benoît Kornmann\, ETHZ\, Zurich (CH)\nBIOENGINEERING SE
 MINARAbstract:\nOrganelles are separate but not isolated intracellular com
 partments. Their positions within the cell establish a cellular geography 
 that creates subcellular microdomains for localized intracellular signalin
 g. In particular\, interfaces between organelles are sites of information 
 and metabolite exchange that play important roles in cellular physiology. 
 They allow\, for instance\, the proper partitioning of lipids between the 
 various cellular membranes. How are these subcellular territories establis
 hed? How do organelles find and maintain their appropriate subcellular pos
 ition? How and why do organelles come into contact with each other? How do
  they manage to do so harmoniously\, without encroaching on each other's t
 erritories and without clashes and entanglements?\nWe use mitochondria as 
 a model organelle to tackle these questions. Mitochondria are neither able
  to synthesize lipids\, nor to receive lipids by vesicular transport. The 
 biogenesis of their membranes depends on contacts established with other o
 rganelles. Moreover\, mitochondria form a dynamic network\, that must main
 tain homeostasis in the constantly moving environment of the cytoplasm.\nI
  will present our research showing how organelles form a plastic lipid exc
 hange network\, how mitochondria hitchhike on the cytoskeleton after mitos
 is\, and how mitochondria avoid tying knots in the crowded and moving intr
 acellular space.Bio:\nDr. Kornmann received a BSc in biology from the Univ
 ersity of Geneva in 1997 and an MSc from the same university in 1998. The 
 University of Geneva awarded him an MPhil in 2001 and a doctorate in 2005.
 \nHe subsequently worked as a postdoc at the University of California\, Sa
 n Francisco\, USA\, under Professor Peter Walter. From 2007 to 2009 with a
 n SNSF grant for young researchers and from 2009 to 2011 with a scholarshi
 p for advanced researchers.\nHe is Assistant Professor of Cell-Organelle B
 iology (SNSF Fellowship) in the Department of Biology (D-BIOL) at ETH Zuri
 ch since 2012.
LOCATION:SV1717a http://map.epfl.ch/?room=sv1717a
STATUS:CONFIRMED
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