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SUMMARY:Spatial Light Interference Microscopy (SLIM): Metrology Meets Biol
 ogy
DTSTART:20150706T121500
DTSTAMP:20260406T214509Z
UID:a40717bf262007cc3084188971e126d8bcbfae912056a3a026e5075d
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Gabriel Popescu\, University of Illinois at Urbana-Champ
 aign\, Urbana\, IL (USA)\nBIO- and MICROENGINEERING SEMINAR(sandwiches ser
 ved)Abstract:\nMost living cells do not absorb or scatter light significan
 tly\, i.e. they are essentially transparent\, or phase objects. Phase cont
 rast microscopy proposed by Zernike in the 1930’s represents a major adv
 ance in intrinsic contrast imaging\, as it reveals inner details of transp
 arent structures without staining or tagging. While phase contrast is sens
 itive to minute optical path-length changes in the cell\, down to the nano
 scale\, the information retrieved is only qualitative. Quantifying cell-in
 duced shifts in the optical path-lengths permits nanometer scale measureme
 nts of structures and motions in a non-contact\, non-invasive manner. Thus
 \, quantitative phase imaging (QPI) has recently become an active field of
  study and various experimental approaches have been proposed.\nRecently\,
  we have developed Spatial Light Interference microscopy (SLIM) as a highl
 y sensitive QPI method. Due to its sub-nanometer pathlength sensitivity\, 
 SLIM enables interesting structure and dynamics studies over broad spatial
  (nanometers-centimeters) and temporal (milliseconds-weeks) scales. I will
  review our recent results on applying SLIM to basic cell studies\, such a
 s intracellular transport\, cell growth\, and single cell tomography. Whit
 e-light diffraction tomography is a recent development that enables SLIM t
 o solve inverse scattering problems and render 3D information with sub-mic
 ron resolution in all directions.Bio:\nGabriel Popescu is an Associate Pro
 fessor in Electrical and Computer Engineering\, University of Illinois at 
 Urbana-Champaign. He authored a book\, edited another book\, 100 journal p
 ublications\, 120 conference presentations\, 24 patents and gave 100 invit
 ed talks. Professor Popescu directs the Quantitative Light Imaging Laborat
 ory (QLI Lab) at the Beckman Institute for Advanced Science and Technology
 . He received the B.S. and M.S. in Physics from University of Bucharest\, 
 in 1995 and 1996\, respectively. He obtained his M.S. in Optics in 1999 an
 d the Ph.D. in Optics in 2002 from the School of Optics/ CREOL (now the Co
 llege of Optics and Photonics)\, University of Central Florida.  Dr. Pope
 scu continued his training with the G. R. Harrison Spectroscopy Laboratory
  at M.I.T.\, working as a postdoctoral associate. He joined University of 
 Illinois at Urbana-Champaign in August 2007. Prof. Popescu received the 20
 09 NSF CAREER Award\, was the 2012 Innovation Discovery Finalist selected 
 by the Office of Technology Management Office\, UIUC\, and was elected as 
 the 2012-2013 Fellow of the Center for Advanced Studies at UIUC. Dr. Popes
 cu is an Associate Editor of Optics Express and Biomedical Optics Express\
 , and Editorial Board Member for Journal of Biomedical Optics. He is an SP
 IE Fellow and an OSA Senior Member. Over the past decade\, Dr. Popescu has
  been working mainly on quantitative phase imaging of cells and tissues\, 
 a very exciting emerging research field on which he published a book in 20
 11. Dr. Popescu founded Phi Optics\, Inc.\, a start-up company that commer
 cializes quantitative phase imaging technology.
LOCATION:SV1717a http://map.epfl.ch/?room=sv1717a
STATUS:CONFIRMED
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