BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Memento EPFL//
BEGIN:VEVENT
SUMMARY:Exploiting nanotools for the development of novel functional assay
 s for membrane proteins
DTSTART:20100205T103000
DTSTAMP:20260510T053610Z
UID:352aafe6d748b08ebecc6e6f07cbc7310a26c8dc92780767f973a6a6
CATEGORIES:Conferences - Seminars
DESCRIPTION:Karen L. Martinez\, Associate Professor\, U Copenhagen\nDue to
  the importance of their physiological functions\, cell membranes represen
 t critical targets in biological research. Membrane proteins\, which make 
 up about one third of the proteome ensure the transduction of the signals 
 across the lipid membrane and the activation of intracellular processes. T
 hus\, the fine-tuning of the cellular response upon stimulation comes from
  a large variety of membrane proteins responding to various external stimu
 li and to their interactions with a myriad of intracellular proteins resul
 ting in a very complex cellular network. Membrane proteins are therefore h
 ighly selective key-players in cell signaling and major drug targets. \n\n
 The last decade has seen the emergence of multiple technological innovatio
 ns to be exploited for the elucidation of biological sensing. Some of them
  appear appropriate for the development of novel membrane proteins based a
 ssays. During my talk\, I will review our three research axes combining su
 ch nanotools with the high selectivity and pharmacology of membrane protei
 ns for the development of novel in vitro and in cell biosensors\, in addit
 ion to fundamental investigations of the biological systems. In particular
 \, I will present our results towards the development of biosensors using 
 nanowires field-effect transistors (bioFET) and the interface of arrays of
  semiconductor nanowires with living cells for cellular biosensing.
LOCATION:BM 3.202
STATUS:CONFIRMED
END:VEVENT
END:VCALENDAR