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SUMMARY:An eco-systems view of complex natural microbiomes
DTSTART:20150907T133000
DTSTAMP:20260528T221010Z
UID:b963a86c05c7a289c5ef66815550a30764faadacb8ed6dfeba6af2c0
CATEGORIES:Conferences - Seminars
DESCRIPTION:Samuel Chaffron\, K.U.Leuven\, Belgium\nRecent advances in seq
 uencing technologies are enabling the extensive characterization of microb
 ial ecosystems at previously unseen scale and resolution. In the oceans\, 
 microbes are dominant drivers of biogeochemical processes\, yet drawing a 
 global picture of functional diversity\, microbial community structure\, a
 nd their ecological determinants remained a grand challenge\, until recent
 ly. In the context of the Tara Oceans project\, we analyzed 7.2 terabases 
 of metagenomic data from samples collected across the globe revealing the 
 wealth of functional diversity in the oceans and identifying environmental
  factors affecting most the bacterial community composition.\nWithin anoth
 er complex ecosystem\, our gut\, there is still a lack of knowledge about 
 the impact of host and environmental variables on microbiota composition w
 ithin an average population. The Flemish Gut Flora Project (FGFP) is as a 
 large-scale cross-sectional fecal sampling effort designed to identify and
  characterize a set of major microbiome-associated variables\, and confoun
 ders\, influencing the human gut microbiome at the population level. Here\
 , exhaustive phenotyping is revealing key factors influencing the gut micr
 obiota composition in a western population. We identified the main drivers
  of microbiota variation and underline the importance of stool consistency
  as a major covariate of microbiota composition. We also observed that tot
 al diversity has not been seen yet\, underlying the importance of specific
  population-level human gut microbiota analyses.
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STATUS:CONFIRMED
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