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SUMMARY:Centromeres impersonating telomeres\, and other forms of deception
  at the chromosome end
DTSTART:20161111T110000
DTEND:20161111T120000
DTSTAMP:20260610T082249Z
UID:a9247bf8bab07a0935d78dee03d320ff4514114730226cc1bdf2ef6a
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Julia Promisel-Cooper\nThe linearity of eukaryotic chromos
 omes is potentially dangerous\, as chromosome ends resemble damage-induced
  DNA breaks and are therefore vulnerable to degradation and fusion\, which
  provoke genome instability. We study the spectrum and mechanisms of telom
 ere function. Recent discoveries include a mode by which telomerase-negati
 ve fission yeast cells use 'generic' heterochromatin to protect chromosome
  ends. We have also expanded the telomeric repertoire\, finding that telom
 eres control meiotic spindle formation and centromere assembly. These prin
 ciples apply to proliferating cells as well\, as centromeres control the d
 ecision to mount mitotic spindle assembly. These studies\, likely applicab
 le beyond fission yeast\, are widening our view of telomere and centromere
  function.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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