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BEGIN:VEVENT
SUMMARY:Personal Regulome Navigation
DTSTART:20161129T110000
DTEND:20161129T120000
DTSTAMP:20260406T212856Z
UID:89e274fd7b3f8c15df2f5b1c391142a0b9bb4d250bec22bf1d5fb491
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Howard Chang\n\nIn biology as in real estate\, location is
  a cardinal organizational principle that dictates the accessibility and f
 low of informational traffic. An essential question in nuclear organizatio
 n is the nature of the address code—how objects are placed and later sea
 rched for and retrieved. Long noncoding RNAs (lncRNAs) have emerged as key
  components of the address code\, allowing protein complexes\, genes\, and
  chromosomes to be trafficked to appropriate locations and subject to prop
 er activation and deactivation. LncRNA-based mechanisms control cell fates
  during development\, and their dysregulation underlies some human disorde
 rs caused by chromosomal deletions and translocations. I will describe a n
 ew technology based on DNA transposition that reveals the epigenomic profi
 les of single cells or from clinical biopsies of disease states. Together 
 these insights are enabling the personal navigation of the gene regulatory
  landscape in health and disease.\n
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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