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SUMMARY:Exploring Fusion Between Electronics and Life Science
DTSTART:20160401T140000
DTSTAMP:20260408T072809Z
UID:86ff399c320e8ad9be009d95c0cfca0b28883ffcf658d0f3a4e5920b
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Yuji Miyahara\, Tokyo Medical and Dental University\, To
 kyo (Jap)\nBIOENGINEERING SEMINARAbstract:\n(Background)\nYuji Miyahara ha
 s been working in the field between electronics and biotechnology for more
  than 30 years. He has developed several types of biosensors\, microTAS an
 d sensing technologies for detection of biomolecules and cell functions. H
 e has been investigating direct interaction between biomolecular charges a
 nd a solid-state devices. Field effect transistors (FETs) have been used t
 o detect biomolecular recognition or cell functions via electrostatic inte
 raction or enzymatic reactions. One of the typical examples of the solid-s
 tate biosensors is FET-based genetic analyses. Genotyping and DNA sequenci
 ng have been demonstrated in combination with single-base extension reacti
 on.\nWe also propose an oocyte-based field effect transistor (oocyte-based
  FET) for drug transport analysis\, in which target transporters are expre
 ssed at the cell membrane of the oocyte. Non-destructive monitoring of the
  uptake kinetics of substrates mediated by membrane-bound transporters can
  be realized with oocyte-based FET. Discrimination of transporting ability
  among genotypes of the transporters could be realized using the oocyte-ba
 sed FET.\nThe bio-FET platform is suitable for a simple\, miniaturized and
  inexpensive system for biomarker detection and high-throughput analysis i
 n clinical diagnostics and molecular biology.Bio:\nEducation:\n1980   B.
  Eng.\, Faculty of Engineering\, Tokyo Institute of Technology\, Dept. of 
 Electrical and Electronics Engineering\n1982   M. Eng.\, Graduate school
  of Science and Engineering\, Tokyo Institute of Technology\, Dept. of Ele
 ctrical and Electronics Engineering\n1985   Ph.D. from Tokyo Institute o
 f Technology\nAppointments\n1985   Central Research Laboratory\, Hitachi
  Ltd.\n1988 - 1989   Visiting researcher at Dept. of Organic Chemistry\,
  ETH Zürich\n1998   Vice manager of Biosystem research department\, Cen
 tral Research Laboratory\, Hitachi Ltd.\n2002   Director of Bioelectroni
 cs group\, National Institute for Materials Science (NIMS)\n2008 - 2010 
   Managing Director\, Biomaterials Center\, NIMS\; Principal Investigator
 \, MANA\, NIMS\n2010 – present   Professor\, Institute of Biomaterials
  and Bioengineering\, Tokyo Medical and Dental University (TMDU)\n2014 - p
 resent   Director\, Institute of Biomaterials and Bioengineering\, TMDU\
 nYuji Miyahara received the Prize of Progress from The Institute of Electr
 ical Engineers of Japan in 2005\, and the Yamazaki Teiichi Prize from Foun
 dation for Promotion of Material Science and Technology of Japan in 2006.
LOCATION:SV1717.1 http://map.epfl.ch/?room=sv1717.1
STATUS:CONFIRMED
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