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SUMMARY:A role for regulated cell polarity in defining growth vectors in t
 he developing skeleton
DTSTART:20090605T121500
DTSTAMP:20260406T170455Z
UID:8a97cd921b838c1317a02da2e5b16a8486c6d54d91d994572242b453
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Andrew Dudley\, PhD Northwestern University/BMBCB Evanst
 on\, IL (USA)\nAbstract : One remarkable feature of growing long bones is 
 the arrangement of flattened chondrocytes in columns arrayed parallel to t
 he axis of growth. These chondrocyte columns elongate via convergent exten
 sion by cell intercalation\, a process regulated by noncanonical Wnt/frizz
 led signaling. We propose that regional differences in chondrocyte stackin
 g provides one mechanism that generates the unique morphologies of individ
 ual bones.
LOCATION:Salle SV 1717a
STATUS:CONFIRMED
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