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SUMMARY:Protein Cages as Theranostic Agent Carriers
DTSTART:20160617T150000
DTSTAMP:20260929T070641Z
UID:6894f6dae6a4a5ab6887f65fbb985332657f65287023a4a108e4c838
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Sierin Lim\, Nanyang Technological University\, Singapor
 e\nBIOENGINEERING SEMINARAbstract:\nProtein cages can be engineered to tai
 lor its function as carriers for therapeutic and diagnostic agents. They a
 re formed by self-assembly of multiple subunits forming hollow spherical c
 age structures of nanometer size. Due to their proteinaceous nature\, the 
 protein cages allow facile modifications on its internal and external surf
 aces\, as well as the subunit interfaces. Modifications on the internal an
 d the external surfaces allow conjugation of small molecule drugs or contr
 ast agent and targeting ligands\, respectively. The subunit interaction is
  of special interest in engineering controlled release property onto the p
 rotein cage. In this presentation\, I will focus on a protein cage represe
 ntative that is ferritin from Archaeoglobus fulgidus as an MRI contrast ag
 ent and a multiple display platform for potential vaccine application.Bio:
 \nSierin Lim is an associate professor of bioengineering and the Assistant
  Chair (Research) at the School of Chemical and Biomedical Engineering\, N
 anyang Technological University (NTU) Singapore. She earned her B.S. in Ch
 emical Engineering and Ph.D. in Biomedical Engineering from University of 
 California Los Angeles (UCLA) and did a postdoc at University of Californi
 a Irvine Department of Chemical Engineering and Materials Science.\nHer Bi
 oengineered and Applied Nanomaterials Laboratory (BeANs Lab) at NTU focuse
 s on the design and engineering of hybrid nano/microscale devices from bio
 logical parts by utilizing protein engineering as a tool for applications 
 in medicine (therapeutics\, diagnostics\, and vaccine)\, energy\, cosmetic
 s\, and food. She is the founding chair and advisor to the Biomedical Engi
 neering Society (Singapore) Student Chapter and is one of the STEM ambassa
 dors at Singapore Committee for UN Women. She is also serving on the edito
 rial board of Frontiers in Bioengineering and Biotechnology and advisory b
 oard of biotechin.asia. In 2012 she received the Asia Pacific Research Net
 working Fellowship from the International Federation for Medical and Biolo
 gical Engineering (IFMBE) and in 2013 the L’Oréal-UNESCO Singapore for 
 Women in Science National Fellowship.
LOCATION:AI 1 153 http://map.epfl.ch/?room=ai1153
STATUS:CONFIRMED
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