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SUMMARY:BioArtificial Hydrogels for Regenerative Medicine
DTSTART:20160822T121500
DTSTAMP:20260509T193331Z
UID:7729dc8a6f6d5894d0833dcde619f15d37e1c74c8d62d2f52baec4cf
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Andrés J. García\, Georgia Institute of Technology\, A
 tlanta\, GA\, (USA)\nDISTINGUISHED LECTURE IN BIOLOGICAL ENGINEERING(sandw
 iches served)Abstract:\nHydrogels\, highly hydrated cross-linked polymer n
 etworks\, have emerged as powerful synthetic analogs of extracellular matr
 ices for basic cell studies as well as promising biomaterials for regenera
 tive medicine applications. A critical advantage of these synthetic matric
 es over natural networks is that bioactive functionalities\, such as cell 
 adhesive sequences and growth factors\, can be incorporated in precise den
 sities while the substrate mechanical properties are independently control
 led. We have engineered poly(ethylene glycol) [PEG]-maleimide hydrogels to
  study epithelial morphogenesis and identified independent contributions o
 f biophysical and biochemical properties of these materials to this develo
 pmental process. In another application\, we have developed synthetic hydr
 ogels that support improved pancreatic islet engraftment\, vascularization
  and function in diabetic models. These studies establish these biofunctio
 nal hydrogels as promising platforms for basic science studies and biomate
 rial carriers for cell delivery\, engraftment and enhanced tissue repair.B
 io:\nEducation\n    Ph.D.\, University of Pennsylvania\, 1996\n    M
 .S.E.\, University of Pennsylvania\, 1992\n    B.S.\, Cornell Universit
 y\, 1991Research Areas and Descriptors:\nBioengineering\; Engineered bioma
 terials and biotherapeutic/cell-delivery vehicles for regenerative medicin
 e applications\, including bone repair\, vascularization\, and inflammatio
 n\, including arthritis. Mechanisms regulating cell adhesive forces.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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