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SUMMARY:Labs\, Cells and Organs on a Chip
DTSTART:20160901T120000
DTSTAMP:20260509T225824Z
UID:e822484e5d776e820278516470639604e66ffd1826d8e8973cc57184
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Albert van den Berg\, University of Twente\, Twente (NL)
 \njoint BIO- and MICROENGINEERING SEMINAR\n (part of IMT Distinguished Le
 cture Series)Abstract:\nThe recent rapid developments in microfluidics tec
 hnologies has enabled the realization of miniaturized laboratories. These 
 Labs-on-a-Chip will play an important role in future medicine\, both in po
 int-of-care devices for drug or biomarker monitoring\, as well as in early
  diagnostic devices. We developed a pre-filled ready-to-use capillary elec
 trophoresis platform for measuring ions in blood. It is used to monitor li
 thium in finger-prick blood of manic-depressive patients\, but can also be
  used for measuring calcium in blood for prevention of milk fever\, or for
  measuring creatinine in blood or sodium in urine for early detection of E
 SRD. Microfluidics can also be exploited to manipulate and experiment with
  cells on chip. We have developed a microsystem for sperm analysis and sel
 ection for artificial insemination\, where we can electrically detect and 
 sort healthy sperm cells. Using microdevices we have been able to electrop
 orate and transfect genes into individual cells\, and a microdroplet platf
 orm was used for encapsulation of single cells in microdroplets\, ordering
  of these microdroplets and 1:1 fusion of these droplets to form hybridoma
 s. We believe this is a very powerful new tool that can be used for high-t
 hroughput single cell experimentation. Apart from diagnostic and cell mani
 pulation devices\, microfluidic devices are increasingly used to realise a
 dvance disease and organ-models\, as illustrated by the blood-brain barrie
 r chip and a blood vessel on a chip to study atherosclerosis.Bio:\nAlbert 
 van den Berg received his MSc in applied physics in 1983\, and his PhD in 
 1988 both at the University of Twente\, the Netherlands. From 1988-1993 he
  worked in Neuchatel\, Switzerland\, at the CSEM and the University (IMT) 
 on miniaturized chemical sensors. In 1998 he was appointed as part-time pr
 ofessor “Biochemical Analysis Systems”\, and later in 2000 as full pro
 fessor on Miniaturized Systems for (Bio)Chemical Analysis in the faculty o
 f Electrical Engineering and part of the MESA+ Institute for Nanotechnolog
 y. In 1994 he initiated together with Prof. Bergveld the international Mic
 roTAS conference series. He published over 400 peer reviewed publications 
 (H=52) a.o. in Science\, Nature\, PNAS\, NanoLetters etc. He received seve
 ral honors and awards such as Simon Stevin (2002)\, two ERC Advanced (2008
 \, 2015) and three ERC Proof of Concept (2011\, 2013\, 2016) grants\, Simo
 n Stevin award (engineering sciences)\, Spinoza prize (2009)\, Honorary Un
 iversity Professorship (Twente\, 2010)\, Distinguished Professor at South 
 China Normal University (SNCU\, 2012) and board member of the Royal Dutch 
 Academy of Sciences (KNAW) (2011-2016). In 2014 he was appointed scientifi
 c director of the MIRA institute for Biomedical Engineering.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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