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SUMMARY:Macrophages During Skeletal Muscle Regeneration: Role of ROS & Sec
 reted Molecules
DTSTART:20160926T094500
DTEND:20160926T104500
DTSTAMP:20260928T185000Z
UID:e0b8d592c8719b7f8187fa45a1686d6d751c6df72e80a370d8687316
CATEGORIES:Conferences - Seminars
DESCRIPTION:Dr. Emmeran Le Moal\, University Claude Bernard Lyon 1 (Franc
 e)\nSEMINAR of the LAUSANNE INTEGRATIVE METABOLISM and NUTRITION ALLIANCE 
 (LIMNA)\n\nAbstract:\nSkeletal muscle has the remarkable ability to regene
 rate following injury. This property is mainly due to a muscle stem cell (
 MuSC) population known as satellite cells. Among cell types observed withi
 n the injured muscle are macrophages\, described to modulate the regenerat
 ive process. This is notably the case of macrophages that sequentially dis
 play distinct phenotypes. First\, damage-associated macrophages clean cell
 ular debris and release pro-inflammatory mediators that stimulate MuSC pro
 liferation. These macrophages then skew their phenotype to restorative mac
 rophages that secreted anti-inflammatory cytokines and molecules that supp
 ort myogenic cell differentiation and fusion.\n\nIn this seminar\, I will 
 present new macrophage-derived candidates involved in the control of skele
 tal muscle regeneration.
LOCATION:AI 1 153 http://map.epfl.ch/?room=ai1153
STATUS:CONFIRMED
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