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SUMMARY:BMI Seminar // Microcircuits in the basal nucleus of the amygdala
DTSTART:20170405T123000
DTEND:20170405T133000
DTSTAMP:20260506T084457Z
UID:a07650f62394f2f421f4b2e6ba4ea2840d962a20125fbe72bd614175
CATEGORIES:Conferences - Seminars
DESCRIPTION:Norbert Hájos\, Laboratory of Network Neurophysiology\, Insti
 tute of Experimental Medicine\, Hungarian Academy of Sciences\, Budapest\,
  Hungary\nThe basal nucleus of the amygdala (BA)\, a cortical structure is
  one of the main output stations of the amygdala region. This area plays a
 n essential role in several higher order cognitive functions\, including f
 ear memory processes\, decision making or social interactions. In spite of
  a fundamental role of the BA in both normal and pathological operation\, 
 our knowledge of its microcircuit organization is surprisingly limited. Th
 is statement is particularly true for amygdalar GABAergic circuits\, which
  are critically involved in controlling principal neuron functions\, and t
 hus\, the amygdalar operation. We identified three interneuron types that 
 provide the vast majority of GABAergic inputs onto the perisomatic region 
 of amygdalar principal neurons. By using high resolution confocal microsco
 py\, electron microscopy and in vitro electrophysiological methods combine
 d with optogenetics\, we uncovered the wiring principles between principal
  neurons and the perisomatic region-targeting interneurons as well as amon
 g these GABAergic cell types. As the local principal neurons distinctly ac
 tivate perisomatic inhibitory neurons\, our data suggest fundamentally dif
 ferent functions for these GABAergic cells in amygdalar network operations
 .
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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