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SUMMARY:Listeria and listeriosis: new insights into a fascinating infectio
 us process
DTSTART:20090403T153000
DTSTAMP:20260916T224300Z
UID:599844f016d991cc5382ada07d7a4fce10019a981e014e9b591d7f0b
CATEGORIES:Conferences - Seminars
DESCRIPTION:Pascale Cossart\nListeria monocytogenes is an ubiquitous bacte
 rium that can contaminate food products and induce several forms of a dise
 ase called listeriosis\, an infection which is mortal in 30% of the cases.
  Infection is mainly due to the capacity of the organism to live and repli
 cate in both phagocytic and non phagocytic cells. It is also due to the pr
 operty of the organism to be able to cross three host barriers during infe
 ction\, the intestinal barrier\, the blood brain barrier and in pregnant w
 omen the materno-fetal barrier. A series of approaches have highlighted th
 at this bacterium has evolved tightly regulated mechanisms to switch from 
 saprohytic life to virulence\, to escape early innate host immune defense\
 , to invade non phagocytic cells\, to spread from cell to cell and  to cro
 ss host barriers. Recent progress in our understanding of the mechanisms u
 sed by Listeria in these different steps have helped discovering new gener
 al concepts in infection biology and cell biology\, sometimes against well
  established dogmas !
LOCATION:SV 1717a
STATUS:CONFIRMED
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