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SUMMARY:Glassy Carbon Microelectrodes for High Charge Injection\, High Sta
 bility and Low Noise Neural Interfaces
DTSTART:20161020T100000
DTEND:20161020T110000
DTSTAMP:20261001T181124Z
UID:ff074213cf7a93abb0b7f8377da5ae29b2343d6b1bc8ddcd9b902329
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Sam Kassegne\, San Diego State University\, CA\, USA.\nF
 or neural applications\, materials that are capable of interfacing with th
 e brain and spinal cord without harming them while recording high-fidelity
  signals over long-term are still sought after. In this talk\, we report o
 n a new electrode material fabricated from lithographically patterned glas
 sy carbon (GC) that promises to achieve this by combining superior electr
 ochemical properties for neural recordings and better long-term stability 
 under electrical stimulation than current thin film metal microelectrodes
 . We demonstrate that lithographically patterned glassy carbon microelectr
 odes can withstand at least 5 million pulses at 0.45mC/cm2 charge density
  with <7.5% impedance change\, have >70% wider electrochemical window and 
 70% higher CTC (charge transfer capacity) than platinum (Pt) microelectro
 des of similar geometry\, which delaminated after 1 million pulses. For di
 rect comparisons\, ultra-flexible\, micro-electrocorticography (μ-ECoG) a
 rrays with GC electrodes were manufactured using recently introduced patt
 ern transfer techniques\, while thin-film platinum arrays were fabricated 
 using conventional microfabrication methods. Additionally\, poly(3\,4-eth
 ylenedioxythiophene)-poly(styrenesulfonate) (PEDOT-PSS) was selectively el
 ectrodeposited on both sets of devices to specifically reduce their impeda
 nces for smaller diameters (<60μm). We observed that PEDOT-PSS adhered si
 gnificantly better to GC than Pt\, presumably due to stronger interaction 
 between GC and carbonaceous PSS-PEDOT chains\, and allowed drastic reducti
 on of electrode size while maintaining same amount of delivered current. F
 urther\, acute in-vivo characterization was performed in rats and it is sh
 own that GC microelectrode arrays recorded somatosensory evoked potentials
  (SEP) with an almost twice SNR (signal-to-noise ratio) when compared to t
 he Pt ones. Supported by characterizations and computational modeling resu
 lts\, the talk will demonstrate (i) the reason behind long-term corrosion 
 problems in thin-film metal microelectrodes and the promise of homogenous 
 electrode material such as GC and (ii) the microenvironment and response o
 f tissues to long-term electrical stimulations. In this talk\, we will als
 o introduce some of the key research activities being carried out at CSNE 
 (Center for Sensorimotor and Neural Engineering)\, NSF-funded Engineering 
 Research Center with University of Washington\, MIT\, and San Diego State 
 University (SDSU) as leading institutions. 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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