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SUMMARY:Synthetic tools for elucidation of the information layer beyond th
 e genome sequence
DTSTART:20161213T171500
DTEND:20161213T183000
DTSTAMP:20260506T080556Z
UID:933bf8351c274343eeb747504e0b34eb821825483bcd50c15d8d8d69
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Andreas Marx - University of Konstanz\nIn eukaryotes\, p
 roteins are often chemically modified during their “life span”. These 
 posttranslational modifications represent an information level that is bey
 ond the genetic code and varies with time and cellular location to allow c
 ells to adjust protein activities to changes in intra- and extracellular c
 onditions. Here\, the protein-based modification ubiquitin and nucleic aci
 d-reminiscent modification poly(ADP-ribose) are of particular interest for
  us. I will report on our recent results in studies of these biopolymers u
 sing synthetic tools. Recent studies have highlighted the paramount import
 ance of “non-standard” Watson-Crick nucleobases in DNA and RNA. I will
  report on our recent results in the aim to develop simplified systems tha
 t allow tracing of these of these rare nucleobases.
LOCATION:BCH 2218 https://plan.epfl.ch/?room==BCH%202218
STATUS:CONFIRMED
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