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BEGIN:VEVENT
SUMMARY:BMI Seminar // Habenular circuits for aversion encoding
DTSTART:20170524T121500
DTEND:20170524T131500
DTSTAMP:20260510T042300Z
UID:a26322e458b5e4a67bd9009b9b5d4c0f8b32c6032e8bc09aabfe9f3d
CATEGORIES:Conferences - Seminars
DESCRIPTION:Manuel Mameli\, Department of Fundamental Neurosciences\, Facu
 lty of Biology and Medicine\, UNIL\, Switzerland\nStress-related experienc
 e trigger circuit reorganisation\, and if persistent contributes to the em
 ergence of depressive symptoms. Therefore understanding the cellular basis
  of stress can ultimately lead to the identification of substrates potenti
 ally relevant for therapeutic interventions for depression. The lateral ha
 benula\, an epithalamic structure\, encode negative stimuli and its dysfun
 ction contributes to aspects of depressive-like phenotypes.\nOur laborator
 y collected evidence indicating that stressors of different nature not onl
 y modify habenular activity but that this occurs via a reduction of inhibi
 tory transmission. I will discuss the cellular event leading to habenular 
 hyperactivity and discuss potential pharmacological or stimulation-based a
 pproaches that might have a therapeutical value.\n \n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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