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SUMMARY:Regulation of adipose tissue plasticity
DTSTART:20170313T133000
DTEND:20170313T143000
DTSTAMP:20260930T193504Z
UID:99323c3c19a745b4a980812d5dc572ac95e03ed1e79a272c13b6b149
CATEGORIES:Conferences - Seminars
DESCRIPTION:Christian WOLFRUM ETH Zürich\, Switzerland\nSEMINAR SERIES: 
  Trends in Physiology and Metabolism (Bio-682)\n\nAbstract:\nBrown adipose
  tissue has received a substantial amount of interest after the discovery 
 of its presence in adult humans as a possible target tissue to increase sy
 stemic energy expenditure and thereby improve metabolic control or even af
 fect weight loss. Brown adipocytes are\, based on current knowledge\, divi
 ded into two classes\, namely the classical brown adipocytes mainly found 
 in rodents in the intrascapular region (iBAT). A second type of brown adip
 ocytes named either beige or brite (brown in white) adipocytes has been de
 scribed in the inguinal white adipose tissue depot (ingWAT). As targeted t
 herapies to induce brown adipose tissue mass and function rely on the know
 ledge of the precise origin of either cell type\, multiple studies have in
 vestigated the formation of brown and brite adipocytes using in vitro as w
 ell as in vivo model systems. The two main pathways leading to increased b
 rown adipose tissue formation are thought to be on the one hand de novo fo
 rmation from precursor cells and on the other hand interconversion from wh
 ite adipocytes. The lecture will focus on origin of white\, brite and brow
 n adipocytes and discuss the current knowledge regarding the function diff
 erences between these types of adipocytes\, as well as their formation in 
 varying physiological conditions.\n\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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