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SUMMARY:BMI Seminar // Sleep spindles - where they come from\, what they d
 o
DTSTART:20171206T121500
DTEND:20171206T131500
DTSTAMP:20260506T190144Z
UID:27b65726dba38e4563deb033eba14d334c00f0199c732b1f4629fc39
CATEGORIES:Conferences - Seminars
DESCRIPTION:Anita Luthi\, Department of Fundamental Neuroscience\, Faculty
  of Biology and Medicine\, University of Lausanne\, Switzerland\nSleep spi
 ndles belong to the best known oscillatory patterns in the EEG that appear
  during periods of drowsiness and non-REM sleep. Spindles are found in all
  mammals and have been linked to sleep architecture\, but also to some of 
 the most pertinent sleep functions\, such as memory consolidation and prot
 ection from environmental stimuli.\nAlthough the sleep spindle is a thalam
 ically generated network event relayed to cortex\, still little is known a
 bout its impact on cortical state and the circuit bases of its multiple fu
 nctions. We recently found that in both mouse and human\, cortical spindle
 -related power during non-REM sleep is organized on an infra-slow time sca
 le (45-50 s) during which sleep’s fragility to sensory stimuli\, sleep-r
 elated signatures of memory consolidation and variations in cardiac activi
 ty are coordinated. Over this time scale\, the elementary needs of sleep t
 o be both\, continous and fragile\, are reconciled. This qualifies sleep s
 pindle dynamics as a hallmark for the sequence of autonomic and central ne
 rvous system states that make up non-REM sleep.\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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