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SUMMARY:NEW AD - BMI Seminar // Optogenetics of arousal and hyperarousal
DTSTART:20170621T121500
DTEND:20170621T131500
DTSTAMP:20260427T201438Z
UID:d0cdf328035ac675b60b9c75816e722b62e79f7e0a24a60f15a60f42
CATEGORIES:Conferences - Seminars
DESCRIPTION:Luis de Lecea\, Department of Psychiatry and Behavioral Scienc
 es\, Stanford University\, USA\nThe arousal construct underlies a spectrum
  of behaviors that include sleep\, exploration\, feeding\, sexual activity
  and adaptive stress. Pathological arousal conditions include stress\, anx
 iety disorders\, and addiction. In the past few years we have used optogen
 etics to interrogate neuronal circuits underlying transitions between arou
 sal states. In particular\, I will talk about how the hypocretin system\, 
 makes the decisions about when to mark the transition between sleep and wa
 kefulness. The dynamics between arousal state transitions are also modulat
 ed by norepinephrine neurons in the locus coeruleus\, histaminergic neuron
 s in the hypothalamus\, dopaminergic neurons in the mesencephalon. I will 
 present data deconstructing some of the circuits associated with hypervigi
 lance..  I will also talk about experiments uncovering a new paradigm to 
 study social arousal and intersubjectivity\, and how optogenetics can assi
 st to map the underpinnings of complex social behavior.\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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