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SUMMARY:Molecular mechanisms of epigenetic regulation
DTSTART:20170911T161500
DTEND:20170911T180000
DTSTAMP:20260313T054703Z
UID:42658eac4dc5c33f8fb56e203d1f7fa65e4da3073646bb8da79c50b1
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Tatiana Kutateladze Department of Pharmacology Universit
 y of Colorado School of Medicine\, Aurora\, Colorado\, USA\nPlant homeodom
 ain (PHD) fingers\, YEATS\, Tudor and bromodomains are found in proteins 
 involved in a wide array of fundamental biological processes\, including 
 transcription\, replication\, DNA damage repair\, cell differentiation a
 nd survival. These domains comprise the largest families of epigenetic re
 aders\, capable of recognizing PTMs (posttranslational modifications) in 
 histones. During her talk\, Prof. Kutateladze will detail the binding mec
 hanisms and biological functions of the readers that select for methylate
 d\, acetylated\, and unmodified histone H3 tails. She will compare specif
 icities and discuss the significance of crosstalk between PTMs and the c
 onsequence of combinatorial readout for the recruitment of these readers 
 to chromatin.\n\nAbout the speaker:\nTatiana Kutateladze\, PhD\, is a Pro
 fessor in the Department of Pharmacology at the University of Colorado Sc
 hool of Medicine. Tatiana received her PhD degree in chemistry from the 
 Moscow State University and obtained a postdoctoral training in biochemis
 try and structural biology in the US. Her research interests include epi
 genetics biology and structural characterization of chromatin-binding pro
 teins implicated in cancer and other human diseases.
LOCATION:SV1717.A https://plan.epfl.ch/theme/generalite_thm_plan_public?re
 quest_locale=fr&room=sv1717a&domain=places&dim_floor=1&lang=fr&dim_lang=fr
 &baselayer_ref=grp_backgrounds&tree_groups=centres_nevralgiques%2Cacce
STATUS:CONFIRMED
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