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VERSION:2.0
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BEGIN:VEVENT
SUMMARY:Structural Biology in vivo by Electron Cryotomography
DTSTART:20170822T110000
DTEND:20170822T120000
DTSTAMP:20260506T053821Z
UID:2c161fc5aa7b7455054782d06d1dc6d376de660183e11ccd8148cb9f
CATEGORIES:Conferences - Seminars
DESCRIPTION:Yi-Wei Chang\, Ph.D.\, California Institute of Technology\, Pa
 sadena\, CA (USA)\nBIOENGINEERING SEMINAR\n\nAbstract:\nElectron cryotomog
 raphy (ECT) enables intact cells to be visualized in 3D in an essentially 
 native state to macromolecular (~4 nm) resolution. It has allowed us to vi
 sualize the structures of macromolecular machines in their native context 
 inside intact cells. In many cases\, such machines cannot be purified inta
 ct for in vitro study. In other cases\, the function of a structure is los
 t outside the cell\, so that the mechanism can be understood only by obser
 vation in situ. In this presentation\, I will use bacterial pilus and secr
 etion systems as examples to show how ECT can help us to understand import
 ant biological processes by doing structural biology in vivo.\n\nBio:\nEdu
 cation:\nNational Tsing Hua University\, Hsinchu\, Taiwan\nPhD\, Structura
 l Biology\n2005 – 2010\n\nPositions held:\nResearch Scientist\nCaliforni
 a Institute of Technology\, Pasadena\, CA (USA)\nJuly 2014 – Present\n\n
 HHMI Research Associate\nHoward Hughes Medical Institute\nJuly 2013 – Ju
 ne 2014\n\nPostdoctoral Scholar\nCalifornia Institute of Technology\, Pasa
 dena\, CA (USA)\nSeptember 2011 – June 2013
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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