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SUMMARY:Cellular therapies for spinal cord injury: what might they achieve
 ?
DTSTART:20171002T110000
DTEND:20171002T120000
DTSTAMP:20260427T220052Z
UID:e47718d70eb9f55c5eadb47c315b60322e3bfe77179ec0a54ef12196
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof John Riddell\, University of Glasgow\, UK.\nSpinal cord i
 njury is a devastating condition leading to loss of sensory\, motor and au
 tonomic function. These functional deficits result from interruption of co
 mmunication between the brain and spinal cord below the injury and are gen
 erally permanent because of the limited capacity of the adult mammalian CN
 S for repair. One biological therapy aimed at promoting repair of the spin
 al cord\, that has now been investigated for several decades and has progr
 essed to clinical translation\, is cell transplantation. This talk will pr
 ovide an overview of cell based therapies for spinal cord injury\, compari
 ng some of the different strategies involving different cell types (differ
 entiated versus stem cells)\, from different sources\, illustrated by exam
 ples from our own studies. The aim will be to provide a realistic perspect
 ive of the potential of cell based therapies for repair and improvement of
  outcome after spinal cord injury.\n\nBio:\nJohn Riddell is a Senior Lectu
 rer at the Institute of Neuroscience and Psychology at the University of G
 lasgow with a research focus on spinal cord function and injury. He obtain
 ed a BSc degree in Physiology from the University of Leeds and PhD in Neur
 ophysiology from the University of Edinburgh. After a post-doctoral positi
 on at University College London and a period working in Sweden on a Wellco
 me Trust Travelling Fellowship he established his own lab at The Universit
 y of Glasgow. His work has contributed to understanding of both sensory an
 d motor spinal circuits and he has a special interest in mechanisms underl
 ying pain states. Spinal cord injury\, and in particular\, preclinical inv
 estigation of the therapeutic potential of cell transplantation strategies
  has been a further main theme of research in the lab over the last 15 yea
 rs. The lab is now also engaged in clinical studies directed at understand
 ing mechanism of pain and plasticity after nervous system trauma\, using a
 pproaches that include fMRI.
LOCATION:H4 2 203.080 https://plan.epfl.ch/?room=H42232.080
STATUS:CONFIRMED
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