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PRODID:-//Memento EPFL//
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SUMMARY:Open-Sourcing DNA Damage Detection for Citizen Science
DTSTART:20171107T193000
DTEND:20171107T203000
DTSTAMP:20260510T064842Z
UID:d16c300c844b165ff75d4a56ed0cbe5610c141c163916385d1c44b10
CATEGORIES:Conferences - Seminars
DESCRIPTION:Rachel Aronoff\, AGiR!\nCitizen science is an exciting way for
  the general public to both participate in research and learn more about i
 ssues of interest. Participation in everything from global investigations 
 to community-driven research can allow people to understand more about how
  science works and sometimes even make a difference. In an effort to provi
 de information and promote research on a new ‘big picture’ concept tha
 t attempts to pull together all the dynamic molecular genetic details of c
 ells - genomic integrity - Rachel Aronoff founded the public service assoc
 iation AGiR! and recently began projects to ‘open- source’ classic met
 hods of DNA damage detection at the open public lab Hackuarium\, which aim
 s to democratise science for all.\n\nTo simplify classic methods to quanti
 tate double-stranded DNA breaks in cells developed in the ‘80s\, the ‘
 comet’ and ‘micronucleus assays\, in order to use primarily ‘kitchen
  sink’ ingredients and provide the possibility for their general use is 
 an important goal of this work. Ultimately\, people would be encouraged to
  determine the baseline levels of micronuclei or comets seen in their own 
 cheek cells\, design a personalized protocol based on the open source guid
 elines\, and measure effects of their chosen intervention (i.e. daily swim
 ming\, running\, or chocolate\, green tea or blueberry consumption). Ex si
 tu experiments for risk analysis are also envisaged.\n\nThese protocols ca
 n provide an easily “workshop-able" way to teach people more about their
  own cells\, while learning how many common activities and products can in
 duce DNA damage. Additionally\, development of a simple flow cell equipped
  with a mini electrophoresis rig for the comet cell assay are planned. If 
 successful\, however\, and international networks of DIT (do-it-together) 
 research groups start accumulating quantitative results using these assays
 \, ‘big data' and security issues would also need to be to be addressed.
  Further info can be found at:\nwww.genomicintegrity.org\nhttp://www.hacku
 arium.ch/en/genomic-integrity/\nhttp://wiki.hackuarium.ch/w/AGiR!_for_geno
 mic_integrity
LOCATION:MED 3 2215 https://plan.epfl.ch/?room=MED32215
STATUS:CONFIRMED
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