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SUMMARY:Microfluidics Neuro-Engineering for Neurological Disorder In Vitro
  Models
DTSTART:20180122T160000
DTSTAMP:20260407T105709Z
UID:65027d831057016abbedfaca58dee1f213a89874470c10509dd11353
CATEGORIES:Conferences - Seminars
DESCRIPTION:Thibault Honegger\, Ph.D.\, CNRS\, Grenoble (F)\nBIOENGINEERIN
 G SEMINAR\n\nAbstract:\nDeveloping minimalistic biological neural networks
  and observing their functional activity is crucial to decipher the inform
 ation processing in the brain. Microfluidic systems have been used to deve
 lop in vitro microenvironments that mimic part of the complexity when stud
 ying in vivo neurological disorders. In this presentation I will highlight
  our approach to use microfluidic systems to bridge the gap between molecu
 lar and network analysis of neural circuits. Using 3D printing technologie
 s and microfluidic neuro-engineering design rules\, I will present the tra
 nslational process to create neural networks of high complexity using comp
 uter aided design\, to fabricate and then to observe physiologically relev
 ant in vitro neural networks. Combined with proper readout of the network 
 functionality using an electro-optical transducer\, such minimalistic envi
 ronments can provide on-demand neural networks and neurological disorder m
 odels for massive drug screening.\n\nBio:\nThibault Honegger graduated fro
 m the Ecole Centrale of Nantes in 2007\, and received his MS degree in Bio
 technologies from University Joseph Fourrier in 2008 and his PhD degree in
  electrical engineering at LTM (CNRS/University Grenoble Alpes) in 2011 on
  3D electrokinetic handling of cancer cells and particles in lab on chip d
 evices. He was a postdoc fellow at the Voldman lab at MIT in 2012 for two 
 years where he developed and investigated axonal guidance using contact le
 ss forces to design neural circuits. He joined CNRS in 2014 as a principal
  investigator in Grenoble to lead the team microfluidics neuro-engineering
 . His current research interests include applications and development of m
 icrotechnologies and microfluidics in neuroscience\, electrical and neural
  interface technologies and smart implantable devices in silk for neural i
 nterfaces. He co-authored 24 peer-reviewed research papers\, 5 granted pat
 ents and 1 book chapter. He is a member of the editor board of IET NanoBio
 Technologies. He founded and is the chairman of the conference Neurofluidi
 cs: Neuroscience & Microfluidics. He co-founded Peerus\, a web app for sci
 entific paper monitoring\, Linkio and Smart Force Technologies.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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