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SUMMARY:Chemical tools for investigating histone deacetylase (HDAC) enzyme
 s
DTSTART:20180227T130000
DTEND:20180227T140000
DTSTAMP:20260919T215350Z
UID:a57e5037aa622d232db074f9f6f5c00defaf6c948aff77f19098d4e7
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Christian Adam Olsen\, University of Copenhagen\nWith a 
 foundation in chemical synthesis\, the laboratory of Christian Olsen explo
 res the function of small molecules\, peptides\, peptidomimetics\, and pro
 teins in biological systems. They are focusing on peptidomimetic secondary
  structures with potential as antimicrobial agents\, as non-proteinogenic 
 ligands for disruption of protein–protein interactions\, and for multiva
 lent display. They are also exploring naturally occurring macrocyclic pept
 ides – and analogues thereof – for development of class- or isoform-se
 lective HDAC inhibitors and quorum sensing modulators\, as well as investi
 gating substrate-specificity of the human lysine deacylase enzymes using c
 hemical biology tools.\n 
LOCATION:BCH 5310 https://plan.epfl.ch/?room==BCH%205310
STATUS:CONFIRMED
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