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SUMMARY:Lausanne Neuroscience Seminar // Multitransmitter neurons – more
  than an oddity
DTSTART:20180502T170000
DTEND:20180502T180000
DTSTAMP:20260916T003934Z
UID:d6342cdfe185069a5dbcbbe87646a591029afeace04dd893b0788473
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Bernardo Sabatini\, Department of Neurobiology\, Harvard
  Medical School\, Boston\, USA\nThe basal ganglia are essential for the ex
 ecution of coordinated goal-oriented movements.  Within these evolutionar
 ily conserved structures\, the activity of dopamine neurons has a privileg
 ed ability to both facilitate the immediate execution of an action as well
  as to increase the future expression of an action associated with reward.
   Here we discuss the circuit and synaptic properties that mediate such e
 ffects.  In particular\, we consider the concerted actions of multiple ne
 urotransmitters released by individual neurons in triggering a coherent do
 wnstream program.  We consider how such multitransmitter programs contrib
 ute to the actions of dopaminergic neurons in the striatum and of basal ga
 nglia output pathways to cortex and lateral habenula.  Our results indica
 te that many fundamental aspects of synaptic transmission\, neurotransmitt
 er identity\, and circuity modulation remain to be discovered.  
LOCATION:DNF UNIL
STATUS:CONFIRMED
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