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SUMMARY:[U.S. DEPARTMENT OF DEFENSE - ALS Therapeutic Idea Award | Researc
 h Funding]
DTSTART;VALUE=DATE:20180622
DTSTAMP:20260916T191120Z
UID:e7a1fe83753519a122fa7f1d2bd06a2d1cd1d1d6cf2207641f316b55
CATEGORIES:Call for proposal
DESCRIPTION:Aim: Through the Congressionally Directed Medical Research Pro
 gram (CDMRP)\, the Department of Defense is announcing the Amyotrophic Lat
 eral Sclerosis (ALS) Research Program Therapeutic Idea Award. This Award w
 ill promote new ideas aimed at drug or treatment discovery that are still 
 in the early stages of development. Development and/or modification of pre
 clinical model systems or the application of high-throughput screens to de
 fine or assess lead compounds for ALS treatment are of interest. Developme
 nt of methods to adequately measure target binding and proximal downstream
  effects (target engagement) and the potential for undesirable activities 
 at related but unintended targets (selectivity) are also encouraged. All p
 roposed research projects should include a well-formulated\, testable hypo
 thesis based on strong scientific rationale that holds translational poten
 tial to improve ALS treatment and/or advance a novel treatment modality.\n
  \nFunding: Maximum USD $500’000\n \nEligibility: Applicants from inte
 rnational organizations or institutions are eligible to apply\, and there 
 are no citizenship restrictions. Applicants must be independent investigat
 ors\, but can come from any academic level.\n \nHow to Apply: Pre-applica
 tions are submitted through the eBRAP platform. They should contain contac
 t information\, a list of collaborators and key personnel\, a preproposal 
 narrative\, and supporting documentation as suggested on the platform. Ful
 l applications (by invitation) will be made via a Grants.gov workspace. Fu
 ll application packages can be downloaded from Grants.gov at any time.\n 
 \nPre-Application Deadline: 22 June 2018\, 5:00 p.m. EST (23:00 CET)\nFull
  Application Deadline: 11 October 2018\, 11:59 p.m. EST (05:59 12 Oct\, CE
 T)\n \nGrants.gov Funding Opportunity Number: W81XWH-18-ALSRP-TIA\n \nFu
 rther information\n\n	To see the program announcement\, navigate to the se
 arch page on Grants.gov and search for the Opportunity Number W81XWH-18-AL
 SRP-TIA\n	For questions about the eBRAP or Grants.gov platforms\, contact 
 the Research Office.\n
LOCATION:
STATUS:CONFIRMED
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