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SUMMARY:Inaugural Lecture // Building the Body with Clocks
DTSTART:20180913T171500
DTEND:20180913T181500
DTSTAMP:20260916T062940Z
UID:db24c1743f906e38c3a73502eccf29256d5af5fc1d690a8edc88db62
CATEGORIES:Inaugural lectures - Honorary Lecture
DESCRIPTION:Prof. Andy Oates\, Institute of Bioengineering\, EPFL\nINAUGUR
 AL LECTURE\n\nAbstract:\nOur own bodies\, like those of most animals\, are
  segmented. This is most obvious in the structure of the backbone\, a row 
 of repeating bony units that supports the body and head. The backbone is f
 ormed sequentially during the embryo’s early development\, each new unit
  being added rhythmically from head to tail. When this process does not wo
 rk properly\, the embryo’s backbone is malformed\, a condition known as 
 congenital scoliosis. Remarkably\, an internal biological clock governs th
 e timing and placement of each new segment. We use the zebrafish as a mode
 l organism to study this process because the zebrafish embryo has prominen
 t segments that are easy to film through a microscope. I will describe the
  work we have done to understand how this clock maintains synchrony amongs
 t its parts\, and how it sends an output signal to make each new body segm
 ent. Our work has revealed a hidden world of microscopic clocks ticking at
  the beginning of each embryo’s life and offers insight into both normal
  development and disease. This basic research has potential applications i
 n both the clinic and engineering.\n\nProgram:\n- Introduction by Prof. Gi
 sou van der Goot\, Dean of Life Sciences\n- Inaugural Lecture\n- apéritif
 \n\nBio:\nAndrew Oates received his PhD at the Ludwig Institute for Cancer
  Research and the University of Melbourne. He did his postdoc at Princeton
  University and the University of Chicago in the lab of Robert Ho\, where 
 he had begun studies on the zebrafish segmentation clock in 1998. In 2003 
 he moved to Germany and started his group at the Max Planck Institute for 
 Molecular Cell Biology and Genetics in Dresden. In 2012 he accepted a posi
 tion at University College London as Professor of vertebrate developmental
  genetics and moved his group to the MRC-National Institute for Medical Re
 search at Mill Hill in London. In April 2015\, he became a member of the F
 rancis Crick Institute in London. In September 2016\, he joined EPFL as a 
 Professor where he now directs the Timing\, Oscillation\, Patterns Laborat
 ory\, composed of biologists\, engineers\, and physicists who use molecula
 r genetics\, quantitative imaging\, and theoretical analysis.\n 
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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