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SUMMARY:Synthetic Approaches to Musculoskeletal Tissue Regeneration
DTSTART:20180517T151500
DTSTAMP:20260501T180121Z
UID:c466a2bcb6e9f28d5afcff5fe4fffe36f081a882c46f32daff987307
CATEGORIES:Conferences - Seminars
DESCRIPTION:Prof. Hala Zreiqat\, University of Sydney (AUS)\nBIOENGINEERIN
 G SEMINAR\n\nAbstract:\nThe repair and regeneration of large bone defects 
 under load has remained a major clinical challenge for orthopaedic surgeon
 s. In addition\, the development of suitable synthetic scaffolds for use a
 s tendon and ligament (T/L) prosthesis to treat T/L ruptures remains a sig
 nificant challenge. This presentation will describe our strategies in synt
 hetic platform to develop cell-free therapeutics to promoting bone and ten
 don regeneration in these challenging situations.\nThis presentation will 
 discuss our three dimensional (3D) printed ceramic scaffold and their effi
 cacy in treating large bone defects under load. Moreover\, we demonstrated
  that manipulating pore size and permeability\, as a function of scaffold 
 architecture\, provides a useful strategy for enhancing bone regeneration 
 outcomes.  The presentation will discuss our engineering solution to deve
 lop synthetic T/L prostheses\, based on fibre-reinforced hydrogels that mi
 mic the hierarchical structure of the native human tendon.  The compositi
 on of this new tendon and ligament allows for high strength and good in vi
 vo tissue integration.\nOur technologies open avenues for skeletal and sof
 t tissue regeneration in various clinical applications.\n\nBio:\nHala Zrei
 qat is a professor of biomedical engineering at the University of Sydney a
 nd both a National Health and Medical Research Council Senior Research Fel
 low (2016-2020)\; Director of the Australian Research Training Centre for 
 Innovative Bio-Engineering\; Co-Director of the Shanghai-Sydney Joint Bioe
 ngineering and Regenerative Medicine Lab at Shanghai JiaoTong\; Honorary P
 rofessor Shanghai Jiao Tong University and Adjunct Professor Drexel Univer
 sity. She is the 2018 New South Wales Premier’s Woman of the Year.\nHer 
 research is on the development of novel engineered materials and 3D-printe
 d platforms for regenerative medicine\, particularly in orthopaedic\, dent
 al\, and maxillofacial applications. She has established national and inte
 rnational industry collaborations to translate her discoveries into approv
 ed medical devices. Her pioneering development of innovative biomaterials 
 for tissue regeneration has led to one awarded (US) and 7 provisional pate
 nts\, and several collaborations with inter/national industry partners.  
 She has been awarded more than $17 M in competitive funding including from
  the NHMRC\, ARC and the NSW Medical Devices Fund. She is the past preside
 nt of the Australian & New Zealand Orthopaedic Research Society\; founder 
 and Chair of the Alliance for Design and Application in Tissue Engineering
  (ADATE) (2006-present)\; founder of IDEAL Society (Inclusion\, Diversity\
 , Equity\, Action Leadership) at Harvard University (October 2017-)\; memb
 er of the National Health and Medical Research Senior Research grant revie
 w panel\, the Australian Research Council Expert College and German Resear
 ch Foundation. Prof. Zreiqat’s overall objective is to advance collabora
 tive research ventures and build educational and industry linkages nationa
 lly and internationally in the field of musculoskeletal disorders and biom
 aterials research.
LOCATION:SV 1717 https://plan.epfl.ch/?room==SV%201717
STATUS:CONFIRMED
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